Your genes may hold the key to safer lung transplants
NCT ID NCT00457847
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
Primary graft dysfunction (PGD) is a serious lung injury that can happen shortly after a lung transplant. This study looks at the DNA of 1,150 lung transplant recipients to see if certain genetic variations make some people more likely to develop PGD. By identifying these genetic risk factors, researchers hope to better understand who is at risk and why.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If genetic risk factors are identified, doctors may one day screen patients before transplant to predict and prevent this serious complication.
- What could go wrong
- This is an observational genetic study, not a treatment trial. It may not find clear genetic links, and even if it does, translating that into prevention will take years.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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