New cancer pill HLX97 enters first human tests

NCT ID NCT07480681

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a new oral drug called HLX97 in 138 people with advanced solid tumors (breast, prostate, or lung cancer) that have stopped responding to standard treatments. The main goals are to check safety, find the right dose, and see if the drug can slow tumor growth. Some participants may also receive a second drug called fulvestrant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HLX97 (a KAT6A/B inhibitor taken as a pill)

What this could lead to

If this trial succeeds, it could point toward a new treatment option for advanced solid tumors like breast, prostate, or lung cancer.

What could go wrong

This is an early Phase 1 trial with only 138 participants, so it is too soon to know if HLX97 is safe or effective. The drug may cause side effects or fail to shrink tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma hormone receptor-positive breast cancer metastatic malignant neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••