New HIV vaccine candidate passes early safety check in small trial

NCT ID NCT05828095

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 27 times

Summary

This early-stage study tested a new HIV vaccine called INO-6160 in 20 healthy adults without HIV. The vaccine uses synthetic DNA to teach the body to recognize HIV and includes an immune booster (IL-12). Some participants also received a booster shot with a different HIV protein. The main goals were to check safety and see if the vaccine triggers an immune response. Results will help design larger studies toward an effective HIV vaccine.

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Contacts and locations

Locations

  • New York Blood Center CRS

    New York, New York, 10065, United States

  • Penn Prevention CRS

    Philadelphia, Pennsylvania, 19104, United States

  • Vanderbuilt Vaccine (VV) CRS

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.