Could a single IV dose of antibodies shield against HIV?

NCT ID NCT06812494

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 34 times

Summary

This study tests whether a combination of three lab-made antibodies, given through an IV, is safe and can help prevent HIV in healthy adults. About 200 participants aged 18-65 will receive the antibodies or a placebo and be followed for 18 months. The goal is to see if this approach can provide a new way to protect against HIV.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ACSA CRS

    NOT_YET_RECRUITING

    Iquitos, Maynas, 1, Peru

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Alabama CRA (Site #31788)

    RECRUITING

    Birmingham, Alabama, 35222, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • BIDMC VCRS (Site ID# 32077)

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bridge HIV, San Francisco Department of Public Health

    RECRUITING

    San Francisco, California, 94102, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Brigham and Women's Hospital Vaccine CRS (BWH VCRS)

    RECRUITING

    Boston, Massachusetts, 02115-6110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CITBM CRS (Site ID 31970)

    RECRUITING

    Callao, 15081, Peru

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chapel Hill CRS (Site #3201)

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chatsworth CRS

    NOT_YET_RECRUITING

    Chatsworth, KwaZulu-Natal, 4030, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Columbia P&S CRS

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fenway Health

    RECRUITING

    Boston, Massachusetts, 02215-4302, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Groote Schuur HIV CRS

    NOT_YET_RECRUITING

    Cape Town, Western Cape, 7925, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instituto de Pesquisa Clinica Evandro Chagas (IPEC) CRS

    RECRUITING

    Rio de Janeiro, 21040-360, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Penn Prevention CRS

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Perinatal HIV Research Unit (PHRU)

    NOT_YET_RECRUITING

    Johannesburg, Gaunteng, 1862, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • San Miguel CRS (Site #11302)

    RECRUITING

    Lima, 32-15088, Peru

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seattle Vaccine and Prevention CRS (Site ID# 30331)

    RECRUITING

    Seattle, Washington, 98104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Setshaba Research Centre

    NOT_YET_RECRUITING

    Soshanguve-H, Soshanguve, 0152, South Africa

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Hope Clinic of the Emory Vaccine Research Center; Emory University

    RECRUITING

    Decatur, Georgia, 30030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pittsburgh CRS (Site 1001)

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Rochester Vaccines to Prevent HIV Infection CRS (Site ID 31467)

    RECRUITING

    Rochester, New York, 14642, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt Vaccine (VV) CRS

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Via Libre (Site ID 31909)

    RECRUITING

    Lima, 15001, Peru

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.