Can a buddy system keep young women HIV-Free? new study aims to find out

NCT ID NCT07666139

Not yet recruiting Prevention Sponsor: RTI International Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study adapts a program called CARES to help 2,100 adolescent girls and young women (ages 16-24) in South Africa and Zimbabwe consistently use HIV prevention methods like pills, rings, or injections. The program includes counseling, text reminders, and peer support. Researchers will see if it helps them get their PrEP refills on time and use it correctly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Comprehensive Adherence Resource and Empowerment Support (CARES) intervention
What this could lead to: If successful, this could provide a practical, low-cost way to help young women consistently use HIV prevention methods, reducing new infections.
What could go wrong: This is an early-stage adaptation study, not a test of a new drug. The intervention may not improve adherence in real-world clinics, and results may vary by location.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV

Contacts and locations

Locations

Desmond Tutu Health Foundation

Cape Town, South Africa
Pangaea Zimbabwe

Harare, Zimbabwe

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