Global hunt for HIV's drug resistance secrets

NCT ID NCT06285110

Summary

This study aims to understand why some HIV treatments fail by examining the virus in people whose medication is no longer working effectively. Researchers collected blood samples from over 1,100 people across 15-20 countries who were taking a common HIV drug (dolutegravir) but still had detectable virus levels. By analyzing the virus's genetic code, they hope to identify specific mutations that cause drug resistance, which could help improve future treatment strategies.

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Contacts and locations

Locations

  • ACONDA Centre de Prise en Charge et de Formation (CePReF)

    Abidjan, Côte d’Ivoire

  • Centre de Traitement Ambulatoire

    Brazzaville, Republic of the Congo

  • Centre de Traitement Ambulatoire

    Pointe-Noire, Republic of the Congo

  • Centre for Infectious Disease Research Zambia (CIDRZ)

    Lusaka, Zambia

  • Centre médical de suivi des donneurs de sang, CNTS

    Abidjan, Côte d’Ivoire

  • Centro Medico Huesped

    Buenos Aires, Argentina

  • HIV-NAT/Thai Red Cross AIDS Research Center (TRCARC)

    Bangkok, Thailand

  • Hopital de Jour du Centre Hospitalier Universitaire (CHU Souro Sanou)

    Bobo-Dioulasso, Burkina Faso

  • Hospital Jamot

    Yaoundé, Cameroon

  • Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

    Mexico City, Mexico

  • Instituto Nacional de Infectiologia Evandro Chagas - Fiocruz

    Rio de Janeiro, Brazil

  • Lighthouse clinic

    Lilongwe, Malawi

  • Martin Preuss Centre

    Lilongwe, Malawi

  • Masaka Regional Referral Hospital / AHF Uganda Cares

    Masaka, Uganda

  • Mbarara University of Science and Technology / Mbarara ISS Clinic (MUST)

    Mbarara, Uganda

  • Moi University, AMPATH

    Eldoret, Kenya

  • National Centre for HIV/AIDS, Dermatology and STDs (NCHADS)

    Phnom Penh, Cambodia

  • National Institute for Medical Research (NIMR)

    Kisesa, Tanzania

  • Newlands Clinic

    Harare, Zimbabwe

  • Ramathibodi Hospital, Mahidol University

    Bangkok, Thailand

  • Regional Hospital Limbe

    Limbe, Cameroon

  • Research for Development, Einstein-Rwanda Research and Capacity Building Program

    Kigali, Rwanda

Conditions

Explore the condition pages connected to this study.