Teens with HIV: does inflammation harm thinking skills?

NCT ID NCT07165639

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether inflammation from HIV affects thinking skills in teens aged 13-19 in Eswatini. Researchers will compare 50 HIV-positive teens on antiretroviral therapy with 30 HIV-negative teens. They will test memory, attention, and processing speed, and measure inflammation markers in blood. The goal is to understand the link between HIV, inflammation, and brain health in adolescents.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could reveal how inflammation from HIV affects brain function in teens, pointing toward ways to protect their thinking skills.

What could go wrong

This is an observational study with only 80 participants, so results may not apply to all teens with HIV. It looks at links, not causes, and may not lead to treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Eswatini Nazarene Health Institution, Baylor College of Medicine Children's Foundation-Eswatini (Centers of Excellence in Mbabane and satellite clinic in Manzini in Raleigh Fitkin Memorial Hospital)

    Manzini, M200, Eswatini

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Email: •••••@•••••