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Does exercise intensity matter for Smokers' hearts and brains?

NCT ID NCT06805968

Knowledge-focused Sponsor: Istanbul Medipol University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This trial looks at how a single session of high-intensity versus low-intensity treadmill exercise affects heart workload, lung function, and thinking skills in female healthcare professionals who smoke. Researchers want to see if harder exercise puts more strain on the heart but offers extra benefits for breathing or mental sharpness. The study involves 30 women and measures things like heart rate, blood pressure, and nicotine dependence.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
treadmill exercise at high or low intensity
What this could lead to
If results are clear, this could help tailor exercise recommendations for smokers to improve cardiovascular health.
What could go wrong
This is a small, single-session study in a specific group, so findings may not apply broadly or predict long-term benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Sep 2023

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Current cigarette smoking, irrespective of nicotine dependence level * Voluntary agreement to participate in the study * Completion of the Fagerström Test for Nicotine Dependence * Absence of a known medical condition that would contraindicate treadmill exercise or interfere with cardiopulmonary assessment Exclusion Criteria: * Diagnosed cardiac or pulmonary disease * Orthopedic, neurological, vestibular, or systemic disease that could affect exercise performance * Use of bronchodilator medication * Orthopedic or cardiopulmonary surgery within the preceding year * Pregnancy * Clinically relevant sensory loss * Leg-length discrepancy that could affect exercise performance * Participation in another clinical study during the preceding month

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Smokers

Contacts and locations

Locations

  • Istanbul Gedik University

    Istanbul, Turkey (Türkiye)

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