Can High-Flow oxygen make heart valve surgery safer for seniors?
NCT ID NCT07059728
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether giving high-flow oxygen through special nasal prongs during a less-invasive heart valve replacement (TAVR) can prevent low oxygen levels and breathing complications. About 452 older adults undergoing TAVR under sedation will be randomly assigned to receive either high-flow or standard low-flow oxygen. The goal is to see if high-flow oxygen reduces serious complications like death, stroke, or kidney injury within 30 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
high-flow nasal oxygen therapy (HFNO)
What this could lead to
If it works, this could make TAVR procedures safer by preventing low oxygen levels and reducing breathing complications during sedation.
What could go wrong
This is a relatively small, early-stage trial focused on a supportive therapy, not a cure. The benefit may be modest and not change overall outcomes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital Clinic de Barcelona
RECRUITINGBarcelona, Barcelona, 08036, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••