Could vitamin c tame anemia? early trial tests high doses in rare blood disorders

NCT ID NCT07612345

First seen May 31, 2026 · Last updated Jun 19, 2026 · Updated 3 times

Summary

This early-stage study tests whether high-dose Vitamin C is safe for people with two rare inherited blood disorders—Pyruvate Kinase Deficiency (PKD) and a form of G6PD deficiency. Both conditions cause red blood cells to break down too quickly, leading to anemia. The study will enroll 3 adults with PKD first, giving them Vitamin C up to three times daily for 3 weeks, while closely monitoring side effects and blood health. If safe, the trial may expand to include more patients and eventually children.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Utah

    Salt Lake City, Utah, 84112, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

anemia, nonspherocytic hemolytic, due to G6PD deficiency G6PD deficiency hemolytic anemia pyruvate kinase deficiency of red cells

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.