Higher dose injection tested for Tough-to-Treat schizophrenia

NCT ID NCT00539071

First seen Nov 01, 2025 · Last updated Apr 07, 2026 · Updated 20 times

Summary

This study tested whether a higher dose of a long-acting injectable antipsychotic medication works better than the standard dose for people with schizophrenia or schizoaffective disorder. It involved 160 participants whose symptoms weren't well-controlled on their current medications. Researchers compared the usual dose (50 mg every two weeks) with higher doses (75-100 mg every two weeks) over six months to see which better improved symptoms.

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Contacts and locations

Locations

  • Vanderbilt Psychiatric Hospital

    Nashville, Tennessee, 37212-8645, United States

Conditions

Explore the condition pages connected to this study.