Could a special diet protect kids with feeding tubes from lung damage?

NCT ID NCT07303868

Not yet recruiting Disease control Sponsor: Boston Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 04, 2026 · Updated 3 times

Summary

This study tests whether foods that bind bile can reduce bile acid levels in the stomach and saliva of children aged 5 to 21 who rely on feeding tubes. High bile levels can lead to lung irritation if accidentally inhaled. For two weeks, participants will eat a high bile-binding diet, then switch to a low bile-binding diet, and their bile levels and symptoms will be compared. The goal is to find a simple dietary way to lower aspiration risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: high bile acid-binding blenderized diet
What this could lead to: If it works, this could point toward a simple dietary change to reduce aspiration-related lung problems in children who rely on feeding tubes.
What could go wrong: This is a small, early-phase trial with only 66 participants, so results may not apply broadly. The diet change is short-term (2 weeks), and long-term benefits or risks are unknown.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASPIRATION FEEDING DIFFICULTIES GASTROSTOMY

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