New hope for bladder cancer patients who Can't take chemo?

NCT ID NCT06963346

First seen Dec 10, 2025 · Last updated Apr 28, 2026 · Updated 20 times

Summary

This early-phase study tested a combination of two drugs—romidepsin and durvalumab—given directly into the bladder for people with muscle-invasive bladder cancer who cannot receive standard chemotherapy. The goal was to find the safest dose and see if the treatment could shrink or eliminate the tumor before surgery. Only 12 participants were planned, but the study is currently on hold.

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Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.