Could a simple scan predict breast cancer drug success?

NCT ID NCT06909604

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new PET imaging method that uses a radioactive tracer to spot HER2 proteins on breast cancer cells. The goal is to see if the scan can predict how well patients will respond to antibody-drug conjugate therapy. Researchers will enroll 50 adults with HER2-positive or low tumors who are receiving neoadjuvant therapy.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Al18F-HER2-BCH (a radioactive tracer for PET imaging)
What this could lead to
If successful, this imaging method could help doctors predict which breast cancer patients will benefit from antibody-drug conjugate therapy, avoiding ineffective treatments.
What could go wrong
This is an early-stage imaging study with only 50 participants, so results may not apply to all patients. The tracer's ability to predict response is not yet proven.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Peking University Cancer Hospital & Institute

    RECRUITING

    Beijing, 100142, China

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