New drug combo aims to outsmart tough cancers

NCT ID NCT06126276

Recruiting now Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is for people with advanced HER2-positive cancers that have come back or spread. It aims to see if taking two targeted drugs together works better than taking one alone to slow or stop cancer growth. About 70 participants will be randomly assigned to one of the two treatment groups to compare results.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Alaska Women's Cancer Care
RECRUITING

Anchorage, Alaska, 99508, United States

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Annie Penn Memorial Hospital
RECRUITING

Reidsville, North Carolina, 27320, United States

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Asplundh Cancer Pavilion
RECRUITING

Willow Grove, Pennsylvania, 19090, United States

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Atrium Medical Center-Middletown Regional Hospital
RECRUITING

Franklin, Ohio, 45005-1066, United States

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Ballad Health Cancer Care - Bristol
RECRUITING

Bristol, Virginia, 24201, United States

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Ballad Health Cancer Care - Kingsport
RECRUITING

Kingsport, Tennessee, 37660, United States

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Benefis Sletten Cancer Institute
RECRUITING

Great Falls, Montana, 59405, United States

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Billings Clinic Cancer Center
RECRUITING

Billings, Montana, 59101, United States

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Bozeman Health Deaconess Hospital
RECRUITING

Bozeman, Montana, 59715, United States

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Bristol Regional Medical Center
RECRUITING

Bristol, Tennessee, 37620, United States

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Cancer Care Center of O'Fallon
RECRUITING

O'Fallon, Illinois, 62269, United States

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Cancer Care Specialists of Illinois - Decatur
RECRUITING

Decatur, Illinois, 62526, United States

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Cancer Center of Western Wisconsin
RECRUITING

New Richmond, Wisconsin, 54017, United States

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Cancer Hematology Centers - Flint
RECRUITING

Flint, Michigan, 48503, United States

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Carle BroMenn Medical Center
RECRUITING

Normal, Illinois, 61761, United States

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Carle Cancer Center
RECRUITING

Urbana, Illinois, 61801, United States

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Carle Cancer Institute Normal
RECRUITING

Normal, Illinois, 61761, United States

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Carle Physician Group-Effingham
RECRUITING

Effingham, Illinois, 62401, United States

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Carle Physician Group-Mattoon/Charleston
RECRUITING

Mattoon, Illinois, 61938, United States

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Carle at The Riverfront
RECRUITING

Danville, Illinois, 61832, United States

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Cedars Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States

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Columbus Oncology and Hematology Associates
RECRUITING

Dublin, Ohio, 43016, United States

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Columbus Oncology and Hematology Associates Inc
RECRUITING

Columbus, Ohio, 43214, United States

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Community Hospital of Anaconda
RECRUITING

Anaconda, Montana, 59711, United States

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Community Medical Center
RECRUITING

Missoula, Montana, 59804, United States

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Community Medical Center
RECRUITING

Toms River, New Jersey, 08755, United States

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Cone Health Cancer Center
RECRUITING

Greensboro, North Carolina, 27403, United States

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Cone Health Cancer Center at Alamance Regional
RECRUITING

Burlington, North Carolina, 27215, United States

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Cone Health Cancer Center at Drawbridge Parkway
RECRUITING

Greensboro, North Carolina, 27410, United States

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Cone Health MedCenter Asheboro
RECRUITING

Asheboro, North Carolina, 27205, United States

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Corewell Health Beaumont Troy Hospital
SUSPENDED

Troy, Michigan, 48085, United States
Corewell Health Dearborn Hospital
SUSPENDED

Dearborn, Michigan, 48124, United States
Corewell Health Farmington Hills Hospital
SUSPENDED

Farmington Hills, Michigan, 48336, United States
Corewell Health William Beaumont University Hospital
SUSPENDED

Royal Oak, Michigan, 48073, United States
Crossroads Cancer Center
RECRUITING

Effingham, Illinois, 62401, United States

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Dayton Physician LLC - Englewood
SUSPENDED

Dayton, Ohio, 45415, United States
Decatur Memorial Hospital
RECRUITING

Decatur, Illinois, 62526, United States

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Delaware Health Center-Grady Cancer Center
RECRUITING

Delaware, Ohio, 43015, United States

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Doctors Hospital
RECRUITING

Columbus, Ohio, 43228, United States

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Dublin Methodist Hospital
RECRUITING

Dublin, Ohio, 43016, United States

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Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States

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Duke Women's Cancer Care Raleigh
RECRUITING

Raleigh, North Carolina, 27607, United States

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Duluth Clinic Ashland
RECRUITING

Ashland, Wisconsin, 54806, United States

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Essentia Health - Deer River Clinic
RECRUITING

Deer River, Minnesota, 56636, United States

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Essentia Health Cancer Center
RECRUITING

Duluth, Minnesota, 55805, United States

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Essentia Health Hibbing Clinic
RECRUITING

Hibbing, Minnesota, 55746, United States

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Essentia Health Sandstone
RECRUITING

Sandstone, Minnesota, 55072, United States

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Essentia Health Virginia Clinic
RECRUITING

Virginia, Minnesota, 55792, United States

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Genesee Hematology Oncology PC
SUSPENDED

Flint, Michigan, 48503, United States
Genesys Hurley Cancer Institute
RECRUITING

Flint, Michigan, 48503, United States

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Grady Memorial Hospital
RECRUITING

Delaware, Ohio, 43015, United States

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Grant Medical Center
RECRUITING

Columbus, Ohio, 43215, United States

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Gundersen Lutheran Medical Center
RECRUITING

La Crosse, Wisconsin, 54601, United States

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Harold Alfond Center for Cancer Care
RECRUITING

Augusta, Maine, 04330, United States

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Hurley Medical Center
RECRUITING

Flint, Michigan, 48503, United States

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Inova Fairfax Hospital
RECRUITING

Falls Church, Virginia, 22042, United States

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Inova Schar Cancer Institute
RECRUITING

Fairfax, Virginia, 22031, United States

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Jersey City Medical Center
RECRUITING

Jersey City, New Jersey, 07302, United States

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John H Stroger Jr Hospital of Cook County
SUSPENDED

Chicago, Illinois, 60612, United States
Kettering Medical Center
SUSPENDED

Kettering, Ohio, 45429, United States
Kootenai Clinic Cancer Services - Post Falls
RECRUITING

Post Falls, Idaho, 83854, United States

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Kootenai Clinic Cancer Services - Sandpoint
RECRUITING

Sandpoint, Idaho, 83864, United States

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Kootenai Health - Coeur d'Alene
RECRUITING

Coeur d'Alene, Idaho, 83814, United States

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Lafayette Family Cancer Center-EMMC
RECRUITING

Brewer, Maine, 04412, United States

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Logan Health Medical Center
RECRUITING

Kalispell, Montana, 59901, United States

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M D Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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MaineHealth Maine Medical Center- Scarborough
RECRUITING

Scarborough, Maine, 04074, United States

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Marshfield Medical Center - Minocqua
RECRUITING

Minocqua, Wisconsin, 54548, United States

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Marshfield Medical Center - Weston
RECRUITING

Weston, Wisconsin, 54476, United States

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Marshfield Medical Center-EC Cancer Center
RECRUITING

Eau Claire, Wisconsin, 54701, United States

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Marshfield Medical Center-Marshfield
RECRUITING

Marshfield, Wisconsin, 54449, United States

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Marshfield Medical Center-Rice Lake
RECRUITING

Rice Lake, Wisconsin, 54868, United States

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Marshfield Medical Center-River Region at Stevens Point
RECRUITING

Stevens Point, Wisconsin, 54482, United States

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Mayo Clinic in Rochester
RECRUITING

Rochester, Minnesota, 55905, United States

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Mercyhealth Cancer Institute - Rockford
RECRUITING

Rockford, Illinois, 61114, United States

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Miami Valley Cancer Care and Infusion
RECRUITING

Greenville, Ohio, 45331, United States

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Miami Valley Hospital
RECRUITING

Dayton, Ohio, 45409, United States

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Miami Valley Hospital North
RECRUITING

Dayton, Ohio, 45415, United States

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Miami Valley Hospital South
RECRUITING

Centerville, Ohio, 45459, United States

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Monmouth Medical Center
RECRUITING

Long Branch, New Jersey, 07740, United States

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Monmouth Medical Center Southern Campus
RECRUITING

Lakewood, New Jersey, 08701, United States

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National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

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NorthShore University HealthSystem-Evanston Hospital
RECRUITING

Evanston, Illinois, 60201, United States

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NorthShore University HealthSystem-Glenbrook Hospital
RECRUITING

Glenview, Illinois, 60026, United States

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NorthShore University HealthSystem-Highland Park Hospital
RECRUITING

Highland Park, Illinois, 60035, United States

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OSF Saint Francis Hospital and Medical Group
RECRUITING

Escanaba, Michigan, 49829, United States

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Ohio State University Comprehensive Cancer Center
RECRUITING

Columbus, Ohio, 43210, United States

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OhioHealth Mansfield Hospital
RECRUITING

Mansfield, Ohio, 44903, United States

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OhioHealth Marion General Hospital
RECRUITING

Marion, Ohio, 43302, United States

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OhioHealth O'Bleness Hospital
RECRUITING

Athens, Ohio, 45701, United States

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OhioHealth Pickerington Methodist Hospital
RECRUITING

Pickerington, Ohio, 43147, United States

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OhioHealth Westerville Medical Campus/Westerville Cancer Center
RECRUITING

Westerville, Ohio, 43082, United States

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OptumCare Cancer Care at Charleston
RECRUITING

Las Vegas, Nevada, 89102, United States

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OptumCare Cancer Care at Fort Apache
RECRUITING

Las Vegas, Nevada, 89148, United States

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OptumCare Cancer Care at Seven Hills
RECRUITING

Henderson, Nevada, 89052, United States

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Premier Blood and Cancer Center
RECRUITING

Dayton, Ohio, 45409, United States

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Providence Portland Medical Center
RECRUITING

Portland, Oregon, 97213, United States

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Providence Saint Vincent Medical Center
RECRUITING

Portland, Oregon, 97225, United States

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Regional Cancer Center at Johnson City Medical Center
RECRUITING

Johnson City, Tennessee, 37604, United States

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Riverside Methodist Hospital
RECRUITING

Columbus, Ohio, 43214, United States

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Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14263, United States

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Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08903, United States

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SIH Cancer Institute
RECRUITING

Carterville, Illinois, 62918, United States

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Saint Alphonsus Cancer Care Center-Boise
RECRUITING

Boise, Idaho, 83706, United States

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Saint Alphonsus Cancer Care Center-Caldwell
RECRUITING

Caldwell, Idaho, 83605, United States

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Saint Alphonsus Cancer Care Center-Nampa
RECRUITING

Nampa, Idaho, 83687, United States

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Saint Alphonsus Cancer Care Center-Ontario
RECRUITING

Ontario, Oregon, 97914, United States

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Saint Francis Medical Center
RECRUITING

Cape Girardeau, Missouri, 63703, United States

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Saint John's Hospital - Healtheast
RECRUITING

Maplewood, Minnesota, 55109, United States

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Saint Joseph Hospital East
RECRUITING

Lexington, Kentucky, 40509, United States

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Saint Luke's Cancer Institute - Boise
RECRUITING

Boise, Idaho, 83712, United States

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Saint Luke's Cancer Institute - Fruitland
RECRUITING

Fruitland, Idaho, 83619, United States

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Saint Luke's Cancer Institute - Meridian
RECRUITING

Meridian, Idaho, 83642, United States

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Saint Luke's Cancer Institute - Nampa
RECRUITING

Nampa, Idaho, 83687, United States

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Saint Vincent Hospital Cancer Center Green Bay
RECRUITING

Green Bay, Wisconsin, 54301, United States

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Saint Vincent Hospital Cancer Center at Oconto Falls
RECRUITING

Oconto Falls, Wisconsin, 54154, United States

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Saint Vincent Hospital Cancer Center at Saint Mary's
RECRUITING

Green Bay, Wisconsin, 54303, United States

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Saint Vincent Hospital Cancer Center at Sheboygan
RECRUITING

Sheboygan, Wisconsin, 53081, United States

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Saint Vincent Hospital Cancer Center at Sturgeon Bay
RECRUITING

Sturgeon Bay, Wisconsin, 54235-1495, United States

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Sanford Bismarck Medical Center
RECRUITING

Bismarck, North Dakota, 58501, United States

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Sanford Broadway Medical Center
RECRUITING

Fargo, North Dakota, 58122, United States

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Sanford Cancer Center Oncology Clinic
RECRUITING

Sioux Falls, South Dakota, 57104, United States

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Sanford Joe Lueken Cancer Center
RECRUITING

Bemidji, Minnesota, 56601, United States

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Sanford Roger Maris Cancer Center
RECRUITING

Fargo, North Dakota, 58122, United States

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Sanford USD Medical Center - Sioux Falls
RECRUITING

Sioux Falls, South Dakota, 57117-5134, United States

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Scott and White Memorial Hospital
RECRUITING

Temple, Texas, 76508, United States

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Southeastern Medical Oncology Center-Clinton
RECRUITING

Clinton, North Carolina, 28328, United States

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Southeastern Medical Oncology Center-Goldsboro
RECRUITING

Goldsboro, North Carolina, 27534, United States

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Southeastern Medical Oncology Center-Jacksonville
RECRUITING

Jacksonville, North Carolina, 28546, United States

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Southern Illinois University School of Medicine
RECRUITING

Springfield, Illinois, 62702, United States

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Springfield Clinic
RECRUITING

Springfield, Illinois, 62702, United States

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Springfield Memorial Hospital
RECRUITING

Springfield, Illinois, 62781, United States

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State University of New York Upstate Medical University
RECRUITING

Syracuse, New York, 13210, United States

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Swedish Medical Center-First Hill
RECRUITING

Seattle, Washington, 98122, United States

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The Angeles Clinic and Research Institute - West Los Angeles Office
RECRUITING

Los Angeles, California, 90025, United States

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Thomas Jefferson University Hospital
RECRUITING

Philadelphia, Pennsylvania, 19107, United States

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Trinity Health IHA Medical Group Hematology Oncology - Brighton
RECRUITING

Brighton, Michigan, 48114, United States

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Trinity Health IHA Medical Group Hematology Oncology - Canton
RECRUITING

Canton, Michigan, 48188, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
RECRUITING

Chelsea, Michigan, 48118, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
RECRUITING

Ypsilanti, Michigan, 48197, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Trinity Health Saint Joseph Mercy Hospital Ann Arbor
RECRUITING

Ann Arbor, Michigan, 48106, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Trinity Health Saint Joseph Mercy Oakland Hospital
RECRUITING

Pontiac, Michigan, 48341, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Trinity Health Saint Mary Mercy Livonia Hospital
RECRUITING

Livonia, Michigan, 48154, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
UC San Diego Health System - Encinitas
RECRUITING

Encinitas, California, 92024, United States

Contact

Contact Phone: •••-•••-••••
UC San Diego Medical Center - Hillcrest
RECRUITING

San Diego, California, 92103, United States

Contact

Contact Email: •••••@•••••
UC San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92093, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
UI Health Care Mission Cancer and Blood - Ankeny Clinic
RECRUITING

Ankeny, Iowa, 50023, United States

Contact

Contact Phone: •••-•••-••••
UI Health Care Mission Cancer and Blood - Des Moines Clinic
RECRUITING

Des Moines, Iowa, 50309, United States

Contact

Contact Phone: •••-•••-••••
UI Health Care Mission Cancer and Blood - Laurel Clinic
RECRUITING

Des Moines, Iowa, 50314, United States

Contact

Contact Phone: •••-•••-••••
UI Health Care Mission Cancer and Blood - Waukee Clinic
RECRUITING

Waukee, Iowa, 50263, United States

Contact

Contact Phone: •••-•••-••••
UM Sylvester Comprehensive Cancer Center at Aventura
RECRUITING

Aventura, Florida, 33180, United States

Contact

Contact Phone: •••-•••-••••
UM Sylvester Comprehensive Cancer Center at Coral Gables
RECRUITING

Coral Gables, Florida, 33146, United States

Contact

Contact Phone: •••-•••-••••
UM Sylvester Comprehensive Cancer Center at Coral Springs
RECRUITING

Coral Springs, Florida, 33065, United States

Contact

Contact Phone: •••-•••-••••
UM Sylvester Comprehensive Cancer Center at Deerfield Beach
RECRUITING

Deerfield Beach, Florida, 33442, United States

Contact

Contact Phone: •••-•••-••••
UM Sylvester Comprehensive Cancer Center at Kendall
RECRUITING

Miami, Florida, 33176, United States

Contact

Contact Phone: •••-•••-••••
UM Sylvester Comprehensive Cancer Center at Plantation
RECRUITING

Plantation, Florida, 33324, United States

Contact

Contact Phone: •••-•••-••••
UPMC Altoona
RECRUITING

Altoona, Pennsylvania, 16601, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
UPMC Cancer Centers - Arnold Palmer Pavilion
RECRUITING

Greensburg, Pennsylvania, 15601, United States

Contact

Contact Phone: •••-•••-••••
UPMC Hillman Cancer Center - Monroeville
RECRUITING

Monroeville, Pennsylvania, 15146, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
UPMC Hillman Cancer Center Erie
RECRUITING

Erie, Pennsylvania, 16505, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
RECRUITING

Mechanicsburg, Pennsylvania, 17050, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
UPMC Western Maryland
RECRUITING

Cumberland, Maryland, 21502, United States

Contact

Contact Phone: •••-•••-••••
UPMC-Magee Womens Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States

Contact

Contact Phone: •••-•••-••••
UPMC-Passavant Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15237, United States

Contact

Contact Phone: •••-•••-••••
UT Southwestern/Simmons Cancer Center-Dallas
RECRUITING

Dallas, Texas, 75390, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Alabama at Birmingham Cancer Center
RECRUITING

Birmingham, Alabama, 35233, United States

Contact

Contact Email: •••••@•••••
University of Illinois
RECRUITING

Chicago, Illinois, 60612, United States

Contact

Contact Phone: •••-•••-••••
University of Kentucky/Markey Cancer Center
RECRUITING

Lexington, Kentucky, 40536, United States

Contact Phone: •••-•••-••••

Contact
University of Maryland/Greenebaum Cancer Center
RECRUITING

Baltimore, Maryland, 21201, United States

Contact

Contact Phone: •••-•••-••••
University of Miami Miller School of Medicine-Sylvester Cancer Center
RECRUITING

Miami, Florida, 33136, United States

Contact

Contact Phone: •••-•••-••••
University of Michigan Health - Sparrow Lansing
RECRUITING

Lansing, Michigan, 48912, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
University of Oklahoma Health Sciences Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Pittsburgh Cancer Institute (UPCI)
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

Contact

Contact Phone: •••-•••-••••
University of South Alabama Mitchell Cancer Institute
RECRUITING

Mobile, Alabama, 36688, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Virginia Cancer Center
RECRUITING

Charlottesville, Virginia, 22908, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Upper Valley Medical Center
RECRUITING

Troy, Ohio, 45373, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
VCU Massey Comprehensive Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Vanderbilt University/Ingram Cancer Center
RECRUITING

Nashville, Tennessee, 37232, United States

Contact

Contact Phone: •••-•••-••••
Walter Reed National Military Medical Center
RECRUITING

Bethesda, Maryland, 20889-5600, United States

Contact

Contact Phone: •••-•••-••••
Wellmont Holston Valley Hospital and Medical Center
RECRUITING

Kingsport, Tennessee, 37660, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
West Virginia University Healthcare
RECRUITING

Morgantown, West Virginia, 26506, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Woodland Cancer Care Center
SUSPENDED

Michigan City, Indiana, 46360, United States

Conditions

Explore the condition pages connected to this study.

MALIGNANT FEMALE REPRODUCTIVE SYSTEM NEOPLASM MALIGNANT SOLID NEOPLASM RECURRENT MALIGNANT FEMALE REPRODUCTIVE SYSTEM NEOPLASM RECURRENT MALIGNANT SOLID NEOPLASM