New drug combo shows promise in shrinking aggressive breast tumors before surgery
NCT ID NCT02326974
First seen Apr 23, 2026 · Last updated May 06, 2026 · Updated 2 times
Summary
This study tested a combination of two drugs, T-DM1 and pertuzumab, given before surgery to people with early-stage HER2-positive breast cancer. The goal was to see if this treatment could completely eliminate the tumor by the time of surgery. The study involved 164 participants with stage II or III breast cancer. Results help doctors understand which patients benefit most from this approach.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Tennessee Oncology/Sarah Cannon Research Institute
Nashville, Tennessee, 37203, United States
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Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, 37232, United States
Conditions
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