New hope for HER2+ breast cancer: drug combo before surgery shows promise

NCT ID NCT07393425

First seen Feb 06, 2026 · Last updated May 12, 2026 · Updated 14 times

Summary

This study tests a new drug combination (trastuzumab deruxtecan plus pertuzumab) given before surgery to shrink tumors in people with HER2-positive breast cancer. If the tumor shrinks enough, they continue the same drugs; if not, they switch to another combo. The goal is to see how many patients have no cancer left at surgery. About 50 women aged 18-70 with stage II-III disease will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Jiaotong University School of Medicine affiliated Ruijin Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.