New light therapy could fade Port-Wine stains

NCT ID NCT05171894

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a treatment called Hemoporfin photodynamic therapy for port-wine birthmarks. It involves injecting a drug that is activated by green light to target the birthmark. 84 adults aged 18 to 75 will receive up to 3 treatment cycles to see which light dose works best and is safest.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hemoporfin (a photosensitizing drug) plus green light

What this could lead to

If successful, this could offer a more effective treatment for port-wine birthmarks, potentially reducing their appearance with fewer sessions.

What could go wrong

This is an early Phase 2 trial with only 84 participants, so results may not apply to everyone. Side effects from the drug and light are possible, and the treatment may not work for all birthmark locations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PORT-WINE BIRTHMARKS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

familial multiple nevi flammei Port-Wine Stain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dermatology Cosmetic Associates of La Jolla, Inc. d/b/a West Dermatology Research Center

    RECRUITING

    San Diego, California, 92121, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Maryland Dermatology, Laser, Skin & Vein Institute

    RECRUITING

    Hunt Valley, Maryland, 21030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Miami Dermatology and Laser Institute

    RECRUITING

    Miami, Florida, 33173, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Luke's University Health Network

    RECRUITING

    Bethlehem, Pennsylvania, 18015, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCI Health Beckman Laser Institute & Medical Clinic

    RECRUITING

    Irvine, California, 92697, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••