Xenon gas vs standard anesthetic: which keeps blood pressure steadier during carotid surgery?

NCT ID NCT00937807

Completed Knowledge-focused Sponsor: Air Liquide Santé International Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed Phase 4 trial tested whether xenon gas (LENOXe) can keep blood pressure as stable as sevoflurane during carotid artery surgery in 84 elderly patients. The study measured blood pressure changes every minute during surgery. Researchers also looked at safety, recovery quality, and pain levels. The goal was to see if xenon is a good alternative for this specific procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: xenon gas
What this could lead to: If xenon proves non-inferior to sevoflurane, it could offer an alternative anesthetic with similar blood pressure stability for elderly patients undergoing carotid surgery.
What could go wrong: This is a small, completed Phase 4 trial with only 84 participants. Results may not apply to broader populations or other surgeries. Xenon is expensive and not widely available.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

carotid stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMODYNAMIC STABILITY

Contacts and locations

Locations

Hospital Pitié-Salpêtrière

Paris, 75013, France

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