Breath monitor could guide surgery care and cut organ failure

NCT ID NCT03852147

Completed Disease control Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether measuring a patient's exhaled gases during surgery can help doctors better manage fluids and medications. 350 adults having major abdominal, orthopedic, or vascular surgery were randomly assigned to standard care or care guided by the respiratory quotient. The goal was to see if this approach reduces organ failure and death within 30 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hemodynamic management algorithm using respiratory quotient measurement
What this could lead to: If successful, this could provide a better way to manage fluids and medications during major surgery, potentially reducing organ failure and complications.
What could go wrong: This is a completed study, but results are not yet widely known. The approach adds complexity and may not improve outcomes over standard care.

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Conditions

The condition(s) this trial relates to.

Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-OP COMPLICATION RESPIRATORY COMPLICATION

Contacts and locations

Locations

BAR

Amiens, 80054, France

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