Can two hours in the heat stress a healthy heart and mind?
NCT ID NCT05575752
First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time
Summary
Researchers at Fudan University are testing what happens to healthy young adults when they sit in a 32°C chamber for two hours. They will measure blood vessel stiffness, lung function, and mental speed, comparing these to a day spent at a comfortable 22°C. The study aims to reveal how a short heat exposure affects the body's systems, which could inform public health advice during hot weather.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- high temperature (32°C) exposure in a chamber
- What this could lead to
- If it works, this could clarify how short heat waves strain the body, pointing to ways to protect people during hot weather.
- What could go wrong
- This is a small, early study in healthy young adults, so results may not apply to older people or those with health conditions. The brief heat exposure may not reflect real-world heat waves.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Oct 2022
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 30 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Living in Shanghai during the study period; * Body mass index \> 18.5 and ≤ 28; * right-handed; * receiving or having received higher education; * with ability to read and understand Chinese smoothly. Exclusion Criteria: * Smoking and alcohol abuse; * Current drug and dietary supplements intake; * Subjects with allergic diseases, such as allergic rhinitis, allergic asthma, and atopy; * Subjects with cardiovascular diseases, such as congenital heart disease, pulmonary heart disease, and hypertension; * Subjects with respiratory diseases, such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease; * Subjects with chronic diseases, such as diabetes, chronic hepatitis, and kidney disease; * Subjects who have a history of major surgery due to the cardiovascular, cerebrovascular, respiratory, or neurological diseases; * Subjects with neurologic disorders, such as stroke, traumatic brain injury, epilepsy, and schizophrenia; * Abnormal spirometry (FEV1 and FVC ≤ 75% of predicted and FEV1/FVC ≤ 0.65); * Subjects with color vision disabilities.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Environmental Health, School of Public Health, Fudan University
Shanghai, Shanghai Municipality, 200032, China
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