New hope for heart transplant patients: drug trial aims to stop rejection
NCT ID NCT03644667
Summary
This study tested whether adding a drug called tocilizumab to standard anti-rejection medications could lead to better results for people who received a heart transplant. Researchers enrolled 385 participants to see if this combination reduced organ rejection, improved heart function, and prevented harmful antibodies from developing in the first year after surgery. The goal was to find a more effective way to help the body accept the new heart while managing the risks of long-term immunosuppression.
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Contacts and locations
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Locations
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Allegheny General Hospital (PAAG)
Pittsburgh, Pennsylvania, 15212, United States
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Baylor University Medical Center (TXTX)
Dallas, Texas, 75246, United States
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Cedars Sinai Medical Center (CACS)
Beverly Hills, California, 90211, United States
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Cleveland Clinic Foundation (OHCC)
Cleveland, Ohio, 44195, United States
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Columbia University Medical Center (NYCP)
New York, New York, 10032, United States
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Duke University Medical Center (NCDU)
Durham, North Carolina, 27710, United States
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Hospital of the University of Pennsylvania (PAUP)
Philadelphia, Pennsylvania, 19104, United States
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Massachusetts General Hospital (MAMG)
Boston, Massachusetts, 02114, United States
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Montefiore Medical Center (NYMA)
The Bronx, New York, 10467, United States
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Mount Sinai Medical Center (NYMS)
New York, New York, 10029, United States
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Northwestern Memorial Hospital (INLM)
Chicago, Illinois, 60611, United States
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Penn State Health: Milton S. Hershey Medical Center (PAHE)
Hershey, Pennsylvania, 17033, United States
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St. Luke's Hospital of Kansas City (MOLH)
Kansas City, Missouri, 64111, United States
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Stanford Health Care (CASU)
Stanford, California, 94305, United States
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Tampa General Hospital (FLTG)
Tampa, Florida, 33606, United States
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Tufts Medical Center (MANM)
Boston, Massachusetts, 02111, United States
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University of California, San Diego: Sulpizio Cardiovascular Center (CASD)
La Jolla, California, 92037, United States
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University of Nebraska Medical Center (NEUN)
Omaha, Nebraska, 68198, United States
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University of Utah (UTMC)
Salt Lake City, Utah, 84132, United States
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Vanderbilt University Medical Center (TNVU)
Nashville, Tennessee, 37232, United States
Conditions
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