New combo therapy aims to jumpstart failing hearts without transplant
NCT ID NCT06965504
First seen Mar 15, 2026 · Last updated May 16, 2026 · Updated 11 times
Summary
This study tests whether a heart pump (Impella 5.5) combined with optimized heart failure medications can help people with severe heart failure and shock recover without needing a transplant or permanent heart assist device. About 250 adults aged 18-79 with a weak heart pump (LVEF ≤40%) and cardiogenic shock will take part. The goal is to see if this approach reduces death, hospital stays, and the need for heart replacement.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
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Locations
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Abbott Northwestern
Minneapolis, Minnesota, 555407, United States
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Atrium Health
Charlotte, North Carolina, 28204, United States
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Centennial Medical Center
Nashville, Tennessee, 32703, United States
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Duke University
Durham, North Carolina, 27710, United States
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Rutgers-Robert Wood Johnson Medical School
New Brunswick, New Jersey, 08901, United States
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Tampa General Hospital
Tampa, Florida, 33606, United States
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University of Pennsylvania Health System
Philadelphia, Pennsylvania, 19104, United States
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Conditions
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