New heart shunt offers hope for stubborn heart failure

NCT ID NCT05686317

Summary

This trial is testing a small, implanted device called the APTURE shunt to see if it helps people with certain types of heart failure who still feel poorly despite taking the best available medications. About 100 participants will be randomly assigned to receive either the real shunt implant or a sham procedure, and neither they nor the doctors assessing them will know which one they got. The main goals are to see if the device is safe and if it improves how patients feel and function over six months.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Abbott Northwestern Hospital

    Minneapolis, Minnesota, 55407, United States

  • Ascension Illinois Heart and Vascular Medical Group

    Elk Grove, Illinois, 60007, United States

  • HCA Houston Healthcare Medical Center

    Houston, Texas, 77004, United States

  • Herz- und Diabeteszentrum NRW - Bad Oeynhausen

    Bad Oeynhausen, 32545, Germany

  • Herzzentrum Dresden GmbH Universitätsklinik für Innere Medizin und Kardiologie

    Dresden, 01307, Germany

  • Herzzentrum Universitätsklinikum Köln

    Cologne, 50937, Germany

  • Inselspital Bern

    Bern, Switzerland, 3010, Switzerland

  • Instituto do Coracao da Universidade de Sao Paulo

    São Paulo, 05403-900, Brazil

  • Johannes Gutenberg Universitaet Mainz

    Mainz, 55131, Germany

  • Kansas University Medical Center

    Kansas City, Kansas, 66160, United States

  • Lankenau Medical Center

    Wynnewood, Pennsylvania, 19096, United States

  • Mayo Clinic

    Rochester, Minnesota, 55902, United States

  • Medical University of South Carolina Charleston

    Charleston, South Carolina, 29425', United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Oklahoma Heart Institute

    Tulsa, Oklahoma, 74104, United States

  • Oregon Health and Science University

    Oregon City, Oregon, 97239, United States

  • Scripps Health

    La Jolla, California, 92037, United States

  • St. Francis Hospital & Heart Center

    Roslyn, New York, 11576, United States

  • St. Michael's Hospital

    Toronto, Canada, M5B 1WB, Canada

  • The Christ Hospital

    Cincinnati, Ohio, 45219, United States

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • The Ottawa Hospital

    Ottawa, Canada, Canada

  • University of California Irvine

    Irvine, California, 92868, United States

  • University of California San Diego

    La Jolla, California, 92027, United States

  • University of California San Francisco

    San Francisco, California, 94143, United States

  • University of Southern California

    Los Angeles, California, 90033, United States

  • Universitätsklinikum Heidelberg Medizinische Klinik

    Heidelberg, 69120, Germany

  • Universitätsspital Basel

    Basel, 4031, Switzerland

Conditions

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