Edwards Lifesciences

This study tests a device called PASCAL that repairs a leaky tricuspid heart valve using a tube inserted through a vein, avoiding open-heart surgery. About 870 people with severe symptoms will be randomly assigned to get the device plus standard medicines, or medicines alone. The…

This study tests a new device called SAPIEN M3 to replace the mitral valve in people with severe mitral regurgitation (a leaky heart valve) who cannot have standard surgery or other treatments. The device is inserted through a vein in the leg, avoiding open-heart surgery. The stu…

This study is testing a new device called the INNOVALVE system to repair leaky mitral valves in people with serious heart valve disease. The device is inserted through a blood vessel, avoiding open-heart surgery. The study includes 65 people who are at high risk for surgery and a…

This study is testing a new monitoring platform called HemoSphere Alta in 100 adults having heart or liver transplant surgery. The goal is to collect data to help improve the device, not to treat a specific condition. Participants must be at least 18 years old and already schedul…

This study collects information from 500 people who receive the INSPIRIS RESILIA aortic valve to see how well it works in real life. Researchers will measure blood flow through the valve and check for any leaks over time. The goal is to understand the valve's long-term performanc…