Heart failure drug trial halted early

NCT ID NCT06237309

Summary

This study tested an experimental drug called REGN5381 in people with chronic heart failure where the heart pumps less effectively. The goal was to check the drug's safety, how it behaves in the body, and its effects on a key heart stress marker. The trial was terminated early and enrolled 89 participants who were already on standard heart failure medications.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AZ Oostende

    Ostend, West Vlaanderen, 8400, Belgium

  • Algemeen Ziekenhuis Groeninge

    Kortrijk, West Vlaanderen, 8500, Belgium

  • Algemeen Ziekenhuis St Jan Brugge Oostende Av

    Bruges, West Flanders, 8000, Belgium

  • Anima Research Center

    Alken, Limburg, 3570, Belgium

  • Arensia Exploratory Medicine Clinic

    Phoenix, Arizona, 85015, United States

  • Arensia Exploratory Medicine Clinic at MBAL Sveta Sofia

    Sofia, 1618, Bulgaria

  • Arensia Exploratory Medicine Clinic at Monza Bucharest

    Bucharest, 11658, Romania

  • Arensia Exploratory Medicine at the Research Institute of Clinical Medicine

    Tbilisi, 0112, Georgia

  • Athens Naval Hospital

    Athens, Attikh, 11521, Greece

  • Centre Hospitalier Regional de la Citadelle

    Liège, 4000, Belgium

  • Clinmedica Research sp zo.o.

    Skierniewice, Łódź Voivodeship, 96-100, Poland

  • Dr M I Sarvan,R Moodley & partners

    Durban, KwaZulu-Natal, 4321, South Africa

  • Edumed

    Jaroměř, 55101, Czechia

  • Fakultni Nemocnice v Motole

    Prague, Central Bohemian, 15006, Czechia

  • First Cardiology Clinic University of Athens

    Athens, Attica, 11527, Greece

  • Flourish Research - Miami (Kendall) (Formerly Clinical Site Partners)

    Miami, Florida, 33186, United States

  • Flourish Research - Orlando (Formerly Clinical Site Partners)

    Winter Park, Florida, 32789, United States

  • General University Hospital Attikon

    Chaïdári, 12462, Greece

  • Grand Hopital de Charleroi

    Gilly, Hainaut, 6060, Belgium

  • Harbor UCLA Medical Center

    Torrance, California, 90509, United States

  • Hospital Arnau de Vilanova

    Valencia, 46015, Spain

  • Hospital Universitario Virgen Macarena Unidad Coronaria 1 planta

    Seville, 41009, Spain

  • Hospital Universitario Virgen de la Arrixaca

    El Palmar, Murcia, 30120, Spain

  • Into Research

    Groenkloof, Gauteng, 0181, South Africa

  • Korea University Guro Hospital

    Seoul, 8308, South Korea

  • Kuils River Hospital

    Kuils River, Western Cape, 7580, South Africa

  • Larissa University Hospital

    Larissa, 41110, Greece

  • MHAT Haskovo

    Haskovo, 6300, Bulgaria

  • Medical University of Lodz

    Lodz, 90-549, Poland

  • Medicus Services s.r.o.

    Brandýs nad Labem-Stará Boleslav, 25001, Czechia

  • NZOZ Gemini

    Żychlin, 62-571, Poland

  • Onze Lieve Vrouw Ziekenhuis Aalst

    Aalst, Oost-Vlaanderen, 9300, Belgium

  • Pmsi Republican Clinical Hospital Timofei Mosneaga

    Chisinau, MD-2025, Moldova

  • Sc Arensia Exploratory Medicine Srl

    Cluj-Napoca, 400006, Romania

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • Severance Hospital at Yonsei University College of Medicine

    Seoul, Seodaemun-gu, 03722, South Korea

  • UCK Medical University of Warsaw

    Warsaw, Masovian Voivodeship, 02-097, Poland

  • UZ Leuven

    Leuven, Vlaams Brabant, 3000, Belgium

  • University Hospital Brno

    Brno, South Moravian, 62500, Czechia

  • University Multiprofile Hospital for Active Treatment Plovdiv

    Plovdiv, 4000, Bulgaria

  • Virgen de las Montañas Hospital

    Villamartín, Cadiz, 11650, Spain

  • Wojewodzki Szpital Zespolony - Ludwik Rydygier Provincial Hospital

    Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland

  • Wonju Severance Christian Hospital

    Wŏnju, Gangwon-do, 26426, South Korea

  • Worthwhile Clinical Trials

    Benoni, Gauteng, 1500, South Africa

Conditions

Explore the condition pages connected to this study.