Heart failure pill showdown: which drug keeps patients alive and out of hospital?

NCT ID NCT03296813

Completed Disease control Sponsor: Duke University Source: ClinicalTrials.gov ↗

Summary

This large study compared two commonly prescribed water pills (diuretics)—torsemide and furosemide—for people hospitalized with heart failure. Nearly 3,000 patients were randomly assigned to take one of these pills after leaving the hospital to see which one worked better. Researchers tracked them for up to a year to find out which medication led to fewer deaths and hospital readmissions.

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Contacts and locations

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Locations

Abington Memorial Hospital

Abington, Pennsylvania, 19001, United States
AtlantiCare Regional Medical Center

Pomona, New Jersey, 08240, United States
Augusta University

Augusta, Georgia, 30912, United States
Baylor University Medical Center

Dallas, Texas, 75246, United States
Black Hills Cardiovascular Research

Rapid City, South Dakota, 57701, United States
Cleveland Clinic

Cleveland, Ohio, 44195, United States
Columbia University Medical Center

New York, New York, 10032, United States
Drexel University College of Medicine

Philadelphia, Pennsylvania, 19102, United States
Duke (Duke Heart Center)

Durham, North Carolina, 27710, United States
Emory Health Care

Atlanta, Georgia, 30322, United States
Fox Valley Clinical Research Center

Aurora, Illinois, 60506, United States
Froedtert Hospital

Milwaukee, Wisconsin, 53226, United States
Good Samaritan Hospital

Ephrata, Pennsylvania, 17522, United States
Greenville Hospital System University Medical Center

Greenville, South Carolina, 29605, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Holy Cross Hospital

Fort Lauderdale, Florida, 33308, United States
Indiana University Health Bloomington Hospital

Bloomington, Indiana, 47402, United States
Indiana University Medical Center

Indianapolis, Indiana, 46202, United States
Inova Health Care Services

Falls Church, Virginia, 22042, United States
Intermountain Medical Center

Murray, Utah, 84107, United States
Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
Kaiser Permanente Medical Center

San Francisco, California, 94115, United States
Lester E. Cox Health Systems

Springfield, Missouri, 65807, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
Main Line Health System

Wynnewood, Pennsylvania, 19096, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61606, United States
Montefore Medical Center - Albert Einstein University Hospital

The Bronx, New York, 10461, United States
Mount Sinai

New York, New York, 10029-6574, United States
New Hanover Regional Medical Center

Wilmington, North Carolina, 28401, United States
North Shore University Hospital

Manhasset, New York, 11030, United States
Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States
Novant Health Matthews Medical Center

Matthews, North Carolina, 28240, United States
Oschner Clinic

New Orleans, Louisiana, 70121, United States
Presbyterian/Brooklyn Methodist Hospital

Brooklyn, New York, 11215, United States
Queens Medical Center

Honolulu, Hawaii, 96813, United States
Russel Medical Center

Alexander City, Alabama, 35010, United States
Saint Francis Hospital and Medical Center

Hartford, Connecticut, 06105, United States
Saint Joseph Mercy Health System / Michigan Heart

Ypsilanti, Michigan, 48197, United States
Sentara Norfolk General Hospital

Norfolk, Virginia, 23507, United States
Shady Grove Medical Center

Rockville, Maryland, 20850, United States
Stony Brook University Hospital

Stony Brook, New York, 11794, United States
The Heart Center, PC

Huntsville, Alabama, 35801, United States
University Hospitals Case Medical Center

Cleveland, Ohio, 44106, United States
University Medical Center

New Orleans, Louisiana, 70112, United States
University of Arizona

Tucson, Arizona, 85724, United States
University of Chicago

Chicago, Illinois, 60637, United States
University of Florida - Gainesville

Gainesville, Florida, 32610, United States
University of Iowa Hospitals and Clinics

Iowa City, Iowa, 52242, United States
University of Michigan Medical Center

Ann Arbor, Michigan, 48109, United States
University of Minnesota

Minneapolis, Minnesota, 55455, United States
University of Mississippi Medical Center

Jackson, Mississippi, 29216, United States
University of North Carolina School of Medicine

Chapel Hill, North Carolina, 27514, United States
University of Utah Hospitals and Clinics

Salt Lake City, Utah, 84132, United States
V.A. Greater Los Angeles Healthcare System

Los Angeles, California, 90073, United States
VA Medical Center/University of Maryland

Baltimore, Maryland, 21201, United States
Virginia Commonwealth University Health

Richmond, Virginia, 23298, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Weill Cornell Medical College

New York, New York, 10021, United States
West Haven VA Medical Center

West Haven, Connecticut, 06516, United States
Yale

New Haven, Connecticut, 06511, United States

Conditions

Explore the condition pages connected to this study.

HEART FAILURE