Could this injection stop your first heart attack?

NCT ID NCT07136012

Recruiting now Prevention Sponsor: Amgen Source: ClinicalTrials.gov ↗

Summary

This large study is testing whether a drug called olpasiran can prevent first major heart problems in people who have high levels of a specific blood fat called lipoprotein(a). It will involve 11,000 adults aged 50+ who have high risk factors for heart disease but have not yet had a heart attack or stroke. Participants will receive either the study drug or a placebo injection to see if it reduces the chance of heart-related death, heart attack, or emergency heart procedures.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

310 Clinical Research
RECRUITING

Inglewood, California, 90301, United States
ARC Biosystems Incorporated
RECRUITING

Vancouver, British Columbia, V6Z 1Y6, Canada
Accellacare Charleston
RECRUITING

Mt. Pleasant, South Carolina, 29464, United States
Accellacare Research of Wilmington
RECRUITING

Wilmington, North Carolina, 28401, United States
Advanced Cardiology Associates
RECRUITING

Rochester Hills, Michigan, 48307, United States
Advanced Cardiovascular LLC
RECRUITING

Alexander City, Alabama, 35010, United States
Advanced Heart and Vascular Institute of Hunterdon
RECRUITING

Flemington, New Jersey, 08822, United States
Advara HeartCare Joondalup
RECRUITING

Joondalup, Western Australia, 6027, Australia
Advara HeartCare Leabrook
RECRUITING

Leabrook, South Australia, 5068, Australia
Advara HeartCare Wesley
RECRUITING

Auchenflower, Queensland, 4066, Australia
Advocate Lutheran General Hospital
RECRUITING

Park Ridge, Illinois, 60068, United States
Aim Research
RECRUITING

Merewether, New South Wales, 2291, Australia
Albany Medical College
RECRUITING

Albany, New York, 12203, United States
Alliance Clinical Research
RECRUITING

San Diego, California, 92120, United States
Alliance For Multispecialty Research - Daphne
RECRUITING

Daphne, Alabama, 36526, United States
Alliance for Multispecialty Research
RECRUITING

Norman, Oklahoma, 73069, United States
Alliance for Multispecialty Research Knoxville
RECRUITING

Knoxville, Tennessee, 37909, United States
Alliance for Multispecialty Research Norfolk
RECRUITING

Norfolk, Virginia, 23502, United States
Alliance for Multispecialty Research, LLC - Park Ridge
RECRUITING

Park Ridge, Illinois, 66068, United States
Alpine Research Organization
RECRUITING

Layton, Utah, 84041, United States
American Institute of Medical Research
RECRUITING

Las Vegas, Nevada, 89123, United States
Apex Research Foundation, LLC
RECRUITING

Jackson, Tennessee, 38301, United States
Ascension Saint Agnes Heart Care
RECRUITING

Baltimore, Maryland, 21229, United States
Ascension Saint Thomas
RECRUITING

Nashville, Tennessee, 37205, United States
Ascension Saint Vincent Heart Center
RECRUITING

Indianapolis, Indiana, 46290, United States
Aultman Cardiology Clinical Trials
RECRUITING

Canton, Ohio, 44710, United States
Baptist Health Care
RECRUITING

Pensacola, Florida, 32514, United States
Basil Clinical
RECRUITING

Inwood, New York, 11096, United States
Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States
Baylor Scott and White Heart and Vascular Hospital-Dallas
RECRUITING

Dallas, Texas, 75226, United States
Birmingham Clinical Research
RECRUITING

Birmingham, Alabama, 35209, United States
Blue Coast Cardiology
RECRUITING

Vista, California, 92083, United States
Brigham and Womens Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
Bryan Heart
RECRUITING

Lincoln, Nebraska, 68506, United States
CB Flock Research Corporation
RECRUITING

Mobile, Alabama, 36608, United States
CIUSSS de l Estrie CHUS Hopital Fleurimont
RECRUITING

Sherbrooke, Quebec, J1H 5N4, Canada
Capitol Cardiology Associates
RECRUITING

Lanham, Maryland, 20706, United States
CardioMetabolic Collaborative Clinic
RECRUITING

Somerset, New Jersey, 08873, United States
Cardiology Associates Research LLC
RECRUITING

Tupelo, Mississippi, 38801, United States
Cardiovascular Research of Northwest Indiana LLC
RECRUITING

Munster, Indiana, 46321, United States
Cardiovascular Specialists of Willowbrook
RECRUITING

Houston, Texas, 77070, United States
Carient Heart and Vascular
RECRUITING

Manassas, Virginia, 20109, United States
Cedar Health Research, LLC
RECRUITING

Dallas, Texas, 75251, United States
Cedar Health Research, LLC
RECRUITING

Euless, Texas, 76040, United States
Centennial Medical Group
RECRUITING

Columbia, Maryland, 21045, United States
Centre de Recherche du Centre Hospitalier de l Universite de Montreal
RECRUITING

Montreal, Quebec, H2W 1T8, Canada
Centricity Research
RECRUITING

Suffolk, Virginia, 23435, United States
Centricity Research Brampton
RECRUITING

Brampton, Ontario, L6S 0C6, Canada
Centricity Research Calgary
RECRUITING

Calgary, Alberta, T2H 2G4, Canada
Chase Medical Research LLC
RECRUITING

Waterbury, Connecticut, 06708, United States
Christie Clinic
RECRUITING

Champaign, Illinois, 61822, United States
Circuit Clinical / Optum Medical Care of New Jersey
RECRUITING

Secaucus, New Jersey, 07094, United States
Circuit Clinical Orchard Park Family Practice
RECRUITING

Orchard Park, New York, 14127, United States
Clearwater Cardiovascular Consultants
RECRUITING

Clearwater, Florida, 33756, United States
Clinical Reseach Philadelphia Pennington
RECRUITING

Hamilton, New Jersey, 08690, United States
Clinical Trials Research - Sacramento
RECRUITING

Roseville, California, 95661, United States
Clinitrials - Mandurah
RECRUITING

Greenfields, Western Australia, 6210, Australia
Clinitrials - Mount Medical Centre
RECRUITING

Perth, Western Australia, 6000, Australia
Columbus Clinical Services LLC
RECRUITING

Miami, Florida, 33125, United States
Concord Repatriation General Hospital
RECRUITING

Concord, New South Wales, 2139, Australia
Core Research Group Pty Ltd
RECRUITING

Milton, Queensland, 4064, Australia
Crystal Run Healthcare
RECRUITING

Monroe, New York, 10950, United States
Denali Health Plant City
RECRUITING

Plant City, Florida, 33563, United States
Diablo Clinical Research
RECRUITING

Walnut Creek, California, 94598, United States
Discovery Clinical Services Ltd
RECRUITING

Victoria, British Columbia, V8T 5G4, Canada
Dr Heart Pty Ltd
RECRUITING

Woolloongabba, Queensland, 4102, Australia
East Coast Institute for Research
RECRUITING

Canton, Georgia, 30114, United States
East Coast Institute for Research, LLC
RECRUITING

Lake City, Florida, 32055, United States
East Texas Cardiology PA
RECRUITING

Houston, Texas, 77002, United States
Eastern Shore Research Institute
RECRUITING

Fairhope, Alabama, 36532, United States
Eclipse Clinical Research
RECRUITING

Tucson, Arizona, 85745, United States
Ecogene-21
RECRUITING

Chicoutimi, Quebec, G7H 7K9, Canada
Edmonton Cardiology Consultants
RECRUITING

Edmonton, Alberta, T5H 4B9, Canada
Elevate Clinical Research KMH Missisauga
RECRUITING

Mississauga, Ontario, L5K 2L3, Canada
Elite Cardiac Research Center LLC
RECRUITING

Hialeah, Florida, 33013, United States
Elite Clinical Studies LLC
RECRUITING

Phoenix, Arizona, 85018, United States
Eminat, LLC
RECRUITING

Miramar, Florida, 33027, United States
Emory University Hospital
RECRUITING

Atlanta, Georgia, 30322, United States
Encompass Clinical Research
RECRUITING

Spring Valley, California, 91978, United States
Epic Clinical Research
RECRUITING

Lewisville, Texas, 75057, United States
Erlanger Health, Inc.
RECRUITING

Chattanooga, Tennessee, 37403, United States
Excel Clinical Research
RECRUITING

Las Vegas, Nevada, 89109, United States
Excel Medical Clinical Trials
RECRUITING

Boca Raton, Florida, 33434, United States
FWD Clinical Research
RECRUITING

Tamarac, Florida, 33321, United States
Flinders Medical Centre
RECRUITING

Bedford Park, South Australia, 5042, Australia
Flourish Research
RECRUITING

Bowie, Maryland, 20715, United States
Focus Clinical Research
RECRUITING

West Hills, California, 91307, United States
Franciscan Health Indianapolis
RECRUITING

Indianapolis, Indiana, 46237, United States
Fraser Clinical Trials
RECRUITING

New Westminster, British Columbia, V3L 3W4, Canada
Fusion Clinical Research
RECRUITING

Norwood, South Australia, 5067, Australia
Gandelman Cardiology, PC
RECRUITING

Greenwich, Connecticut, 06830, United States
Georgia Clinical Research
RECRUITING

Lawrenceville, Georgia, 30044, United States
Graves Gilbert Clinic
RECRUITING

Bowling Green, Kentucky, 42101, United States
Guardian Research Organization LLC
RECRUITING

Winter Park, Florida, 32792, United States
Health East Cancer Care
RECRUITING

Maplewood, Minnesota, 55109, United States
Heart Center Research LLC
RECRUITING

Huntsville, Alabama, 35801, United States
Heart Clinic of Hammond
RECRUITING

Covington, Louisiana, 70433, United States
Heart Health Institute Research Incorporated
RECRUITING

Scarborough Village, Ontario, M1B 4Z8, Canada
Henry Ford Health System
RECRUITING

Detroit, Michigan, 48202, United States
Hero Clinical Research
RECRUITING

Phoenix, Arizona, 85021, United States
Hollywood Private Hospital
RECRUITING

Nedlands, Western Australia, 6009, Australia
HonorHealth Research Institute
RECRUITING

Scottsdale, Arizona, 85258, United States
Hudson Valley Cardiovascular Physicians PC
RECRUITING

Poughkeepsie, New York, 12601, United States
Hutchinson Clinic PA
RECRUITING

Hutchinson, Kansas, 67502, United States
Icahn School of Medicine at Mount Sinai
RECRUITING

New York, New York, 10029, United States
Ima Clinical Research
RECRUITING

Monroe, Louisiana, 71201, United States
Ima Clinical Research
RECRUITING

Austin, Texas, 78745, United States
Ima Clinical Research - Warren
RECRUITING

Warren Township, New Jersey, 07059, United States
Ima Clinical Research Manhattan
RECRUITING

New York, New York, 10036, United States
Ima Clinical Research San Antonio
RECRUITING

San Antonio, Texas, 78229, United States
Indago Research and Health Center
RECRUITING

Hialeah, Florida, 33012, United States
Inova Cardiology - Fairfax
RECRUITING

Fairfax, Virginia, 22031, United States
Inpatient Research Clinic, LLC
RECRUITING

Miami Lakes, Florida, 33014, United States
Institut de recherches cliniques de Montreal
RECRUITING

Montreal, Quebec, H2W 1R7, Canada
Interventional Cardiology Medical Group
RECRUITING

West Hills, California, 91307, United States
InvivoCure
RECRUITING

Los Angeles, California, 91405, United States
Jackson Heart Clinic
RECRUITING

Jackson, Mississippi, 39216, United States
Jacksonville Center for Clinical Research
RECRUITING

Jacksonville, Florida, 32216, United States
Johns Hopkins Hospital
RECRUITING

Baltimore, Maryland, 21287, United States
Johns Hopkins University
RECRUITING

Columbia, Maryland, 21044, United States
K and R Research
RECRUITING

Marion, Ohio, 43302, United States
Kendall South Medical Center
RECRUITING

Miami, Florida, 33175, United States
Las Vegas Clinical Trials
RECRUITING

North Las Vegas, Nevada, 89030, United States
Linear Clinical Research Limited
RECRUITING

Nedlands, Western Australia, 6009, Australia
Louisiana Heart Center
RECRUITING

Slidell, Louisiana, 70458, United States
Lynn Institute of the Ozarks
RECRUITING

Little Rock, Arkansas, 72204, United States
Manshadi Heart Institute
RECRUITING

Stockton, California, 95204, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Med Clinical Research Partners - Irvington
RECRUITING

Irvington, New Jersey, 07111, United States
MediSphere Medical Research Center LLC
RECRUITING

Evansville, Indiana, 47714, United States
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Medication Management LLC
RECRUITING

Greensboro, North Carolina, 27405, United States
Medstar Franklin Square Medical Center
RECRUITING

Hyattsville, Maryland, 20782, United States
MercyOne Iowa Heart Center
RECRUITING

West Des Moines, Iowa, 50266, United States
Methodist Hospital
RECRUITING

Saint Louis Park, Minnesota, 55426, United States
Metropolitan Cardiovascular Consultants LLC
RECRUITING

Beltsville, Maryland, 20705, United States
Midwest Heart and Vascular Specialists
RECRUITING

Overland Park, Kansas, 66211, United States
Momentum Clinical Research - Sunshine
RECRUITING

Melbourne, Victoria, 3021, Australia
Monroe Biomedical Research
RECRUITING

Monroe, North Carolina, 28112, United States
Monroe Research LLC
RECRUITING

West Monroe, Louisiana, 71291, United States
Montreal Heart Institute
RECRUITING

Montreal, Quebec, H1T 1C8, Canada
Monument Health Clinical Research
RECRUITING

Rapid City, South Dakota, 57701, United States
Moses H Cone Memorial Hospital
RECRUITING

Greensboro, North Carolina, 27401, United States
Mount Sinai Queens
RECRUITING

New York, New York, 10029, United States
MyMichigan Medical Center Midland - Clinical Research Department
RECRUITING

Midland, Michigan, 48670, United States
National Heart Institute
RECRUITING

Beverly Hills, California, 90211, United States
New Jersey Medcare / New Jersey Heart
RECRUITING

Linden, New Jersey, 07036, United States
Nexgen Research
RECRUITING

Lima, Ohio, 45801, United States
Niagara Falls Memorial Medical Center
RECRUITING

Niagara Falls, New York, 14304, United States
North Dallas Research Associates
RECRUITING

McKinney, Texas, 75069, United States
North Georgia Clinical Research
RECRUITING

Woodstock, Georgia, 30189, United States
North York Diagnostic and Cardiac Centre
RECRUITING

North York, Ontario, M6B 3H7, Canada
Northeast Georgia Medical Center Wisteria Building
RECRUITING

Cumming, Georgia, 30041, United States
Novatrials
RECRUITING

Charlestown, New South Wales, 2290, Australia
Nsc Research
RECRUITING

Johns Creek, Georgia, 30024, United States
Oakville Cardiovascular Research
RECRUITING

Oakville, Ontario, L6K 3W7, Canada
Ocala Cardiovascular Research
RECRUITING

Ocala, Florida, 34471, United States
Ocala Research Institute, Inc
RECRUITING

Ocala, Florida, 34474, United States
Orange Health Service
RECRUITING

Orange, New South Wales, 2800, Australia
Orion Medical
RECRUITING

Pasadena, Texas, 77505, United States
Ormond Beach Clinical Research
RECRUITING

Ormond Beach, Florida, 32174, United States
Panax Clinical Research
RECRUITING

Miami Lakes, Florida, 33014, United States
Parkview Research Center
RECRUITING

Fort Wayne, Indiana, 46845, United States
Parkway Cardiology Associates
RECRUITING

Oak Ridge, Tennessee, 37830, United States
Partners in Advanced Cardiac Evaluation
RECRUITING

Newmarket, Ontario, L3Y 8C3, Canada
PharmaTex Research, LLC
RECRUITING

Amarillo, Texas, 79106, United States
Pharmacorp Clinical Trials Inc
RECRUITING

Charleston, South Carolina, 29412, United States
Phoenix Clinical
RECRUITING

Phoenix, Arizona, 85014, United States
Piedmont Healthcare
RECRUITING

Statesville, North Carolina, 28625, United States
Pioneer Medical Associates
RECRUITING

Carrollton, Texas, 75007, United States
Pottstown Medical Specialists Inc
RECRUITING

Pottstown, Pennsylvania, 19464, United States
Premier Clinical Trial Network
RECRUITING

Hamilton, Ontario, L8L 5G4, Canada
Prisma Health Carolina Cardiology - Greenville
RECRUITING

Gantt, South Carolina, 29605, United States
Proactive Clinical Research
RECRUITING

Fort Lauderdale, Florida, 33308, United States
Rainier Clinical Research Center
RECRUITING

Renton, Washington, 98057, United States
Rasai Research
RECRUITING

Jackson Heights, New York, 11372, United States
Reid Physician Associates
RECRUITING

Richmond, Indiana, 47374, United States
Renown Institute for Heart and Vascular Health
RECRUITING

Reno, Nevada, 89502, United States
Research Institute of McGill University Health Center - Glen Site
RECRUITING

Montreal, Quebec, H4A 3J1, Canada
Revival Research Institute
RECRUITING

Southfield, Michigan, 48034, United States
Revival Research Institute
RECRUITING

Sherman, Texas, 75092, United States
Royal Prince Alfred Hospital
RECRUITING

Camperdown, New South Wales, 2050, Australia
SMH Cardiology Clinical Trials Incorporated
RECRUITING

Surrey, British Columbia, V3V 0C6, Canada
Saint Michaels Medical Center
RECRUITING

Newark, New Jersey, 07102, United States
Saratoga Clinical Research, LLC
RECRUITING

Saratoga Springs, New York, 12866, United States
Selma Medical Associates
RECRUITING

Winchester, Virginia, 22601, United States
Sisters of Saint Mary Health Heart and Vascular Care
RECRUITING

Bridgeton, Missouri, 63044, United States
Solaris Clinical Research
RECRUITING

Meridian, Idaho, 83646, United States
South Denver Cardiology Associates
RECRUITING

Littleton, Colorado, 80120, United States
Southern Endocrinology Associates PA
RECRUITING

Mesquite, Texas, 75149, United States
St Davids Heart & Vascular PLLC dba Austin Heart
RECRUITING

San Marcos, Texas, 78666, United States
St Lukes Idaho Cardiology Associates
RECRUITING

Meridian, Idaho, 83642, United States
Suburban Hospital
RECRUITING

Bethesda, Maryland, 20814, United States
Suncoast Clinical Research Inc
RECRUITING

New Port Richey, Florida, 34652, United States
Tcr Institute Llc
RECRUITING

Kingwood, Texas, 77339, United States
Tennessee Center for Clinical Trials
RECRUITING

Tullahoma, Tennessee, 37388, United States
Texas Diabetes and Endocrinology
RECRUITING

Austin, Texas, 78731, United States
Texas Institute of Cardiology
RECRUITING

McKinney, Texas, 75071, United States
Texas Tech University Health Sciences Center
RECRUITING

Lubbock, Texas, 79430, United States
The Alfred Hospital
RECRUITING

Melbourne, Victoria, 3004, Australia
The Christ Hospital
RECRUITING

Cincinnati, Ohio, 45219, United States
The Heart House - Washington Township
RECRUITING

Sewell, New Jersey, 08080, United States
The Research Group of Lexington LLC
RECRUITING

Lexington, Kentucky, 40503, United States
Tidewater Physicians Multispecialty Group Clinical Research
RECRUITING

Newport News, Virginia, 23606, United States
Triad Clinical Trials, LLC
RECRUITING

Greensboro, North Carolina, 27410, United States
Tribe Clinical Research - Spartanburg
RECRUITING

Spartanburg, South Carolina, 29301, United States
Tyler Cardiovascular Consultants
RECRUITING

Tyler, Texas, 75701, United States
UCHealth Memorial Central
RECRUITING

Colorado Springs, Colorado, 80909, United States
University of Alabama Birmingham Saint Vincents Birmingham
RECRUITING

Birmingham, Alabama, 35205, United States
University of California San Diego
RECRUITING

La Jolla, California, 92037, United States
University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of The Sunshine Coast Clinical Trials, Sippy Downs
RECRUITING

Sippy Downs, Queensland, 4556, Australia
Valley Clinical Trials
RECRUITING

Northridge, California, 91325, United States
Valley Institute of Research Plano
RECRUITING

Plano, Texas, 75024, United States
Velocity Clinical Research - Cincinnati
RECRUITING

Cincinnati, Ohio, 45219, United States
Victoria Heart Institute Foundation
RECRUITING

Victoria, British Columbia, V8R 1B2, Canada
Victorian Heart Hospital
RECRUITING

Clayton, Victoria, 3168, Australia
Virginia Heart
RECRUITING

Falls Church, Virginia, 22042, United States
Virginia Heart - Loudoun
RECRUITING

Leesburg, Virginia, 20176, United States
Vital Heart and Vein
RECRUITING

Humble, Texas, 77338, United States
Walker Family Care
RECRUITING

Little River, South Carolina, 29566, United States
Washington University
RECRUITING

St Louis, Missouri, 63110, United States
Western Washington Medical Group
RECRUITING

Everett, Washington, 98208, United States
Winchester Medical Center
RECRUITING

Winchester, Virginia, 22601, United States
Zenos Clinical Research
RECRUITING

Dallas, Texas, 75230, United States

Conditions

Explore the condition pages connected to this study.

CARDIOVASCULAR DISEASE