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Heart-Artery test could flag anesthesia blood pressure drops

NCT ID NCT05969886

Diagnosis Sponsor: University Medical Center Ho Chi Minh City (UMC) Source: ClinicalTrials.gov ↗

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Not yet recruiting
Registered, but not yet taking participants.
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Cancelled before anyone took part.

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First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time

Summary

Researchers are studying whether a preoperative heart ultrasound measure called ventricular-arterial coupling can predict dangerously low blood pressure after anesthesia induction. The study enrolls about 475 adults having elective non-cardiac, non-obstetric, non-gynecologic surgery under general anesthesia. Participants have a transthoracic echocardiogram within 48 hours before surgery, and researchers track their blood pressure from anesthesia induction to surgical incision to see who develops post-induction hypotension.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
preoperative transthoracic echocardiography to measure ventricular-arterial coupling
What this could lead to
If the link holds, doctors could use a routine heart ultrasound before surgery to flag patients likely to drop blood pressure under anesthesia and adjust their care.
What could go wrong
This is an observational study, so it can show a link but not prove that acting on the measure prevents low blood pressure. The findings may not apply to other hospitals or patient groups.

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Study facts

What this study's own registry entry says, in plain language.

Participants

475 people

The number who actually took part.

Started

Jul 2023

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with American Society of Anesthesiologists (ASA) physical status 1 - 4 who underwent elective surgery

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients ≥ 18 years old. * Patients with ASA (American Society of Anesthesiologists) physical status 1 - 4. * Elective non-cardiac, non-obstetric, and non-gynaecologic surgery * Preoperative transthoracic echocardiography was performed within 48 hours before surgery. The values of Ees and Ea were determined by the method of Chen. * Patients consented to participate in the study. * Patients scheduled for surgery undergoing standard general anesthesia (protocol: see below) with endotracheal intubation. * Patients were hemodynamically stable until the preoperative period. Exclusion Criteria: • Uncorrected congenital heart disease, moderate-to-severe valvular disease or pulmonary hypertension, arrhythmias, anticipated difficult airway, and known allergy to anaesthetic agents.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypotension on induction

Contacts and locations

Locations

  • University Medical Centre Ho Chi Minh

    Ho Chi Minh City, Vietnam

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