Heart attack prevention showdown: plaque scans vs. blood flow tests

NCT ID NCT07324720

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two strategies for treating people with high-risk coronary artery disease. One strategy uses detailed imaging of plaque inside the arteries to decide which blockages need a stent or bypass. The other uses a standard blood flow test. About 1,944 participants will be randomly assigned to one of the two approaches. The goal is to see which strategy better prevents future heart problems like heart attacks or the need for repeat procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
revascularization procedure (stenting or bypass) guided by either plaque imaging or blood flow testing
What this could lead to
If successful, this could show that using detailed plaque imaging to decide which blockages to treat is as good as or better than the current standard of blood flow testing.
What could go wrong
This is a large trial, but it compares two established approaches, so a dramatic breakthrough is unlikely. The results may not apply to all heart disease patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Seoul National University Hospital

    RECRUITING

    Seoul, Main Building, 03080, South Korea

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