New drug duo aims to boost fight against tough head and neck cancers

NCT ID NCT05366166

Summary

This study is testing whether adding two drugs, pembrolizumab and olaparib, before and after standard chemoradiation can better control a difficult-to-treat form of head and neck cancer. It will involve about 45 adults with locally advanced cancer who have not had prior treatment. The main goal is to see if this combination helps keep the cancer from growing or spreading for at least one year after treatment starts.

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Contacts and locations

Locations

  • Indiana University Simon Comprehensive Cancer Center

    Indianapolis, Indiana, 46202, United States

  • Medical University of South Carolina (MUSC)

    Charleston, South Carolina, 29425, United States

  • UNC Lineberger

    Chapel Hill, North Carolina, 27514, United States

  • University of Louisville, Brown Cancer Center

    Louisville, Kentucky, 40202, United States

Conditions

Explore the condition pages connected to this study.