New hope for Tough-to-Treat head and neck cancers: can a drug duo outperform the standard?

NCT ID NCT06589804

Recruiting now Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is for people with advanced head and neck cancer that has returned or spread and has stopped responding to standard platinum-based chemotherapy. It aims to see if combining two immunotherapy drugs (pembrolizumab and cetuximab) helps patients live longer than using pembrolizumab alone. About 158 participants will be randomly assigned to receive one of the two treatment plans.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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AMG Crystal Lake - Oncology
RECRUITING

Crystal Lake, Illinois, 60014, United States

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AMG Libertyville - Oncology
RECRUITING

Libertyville, Illinois, 60048, United States

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Abbott-Northwestern Hospital
RECRUITING

Minneapolis, Minnesota, 55407, United States

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Advocate Christ Medical Center
RECRUITING

Oak Lawn, Illinois, 60453-2699, United States

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Advocate Good Samaritan Hospital
RECRUITING

Downers Grove, Illinois, 60515, United States

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Advocate Good Shepherd Hospital
RECRUITING

Barrington, Illinois, 60010, United States

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Advocate High Tech Medical Park
RECRUITING

Palos Heights, Illinois, 60463, United States

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Advocate Illinois Masonic Medical Center
RECRUITING

Chicago, Illinois, 60657, United States

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Advocate Lutheran General Hospital
RECRUITING

Park Ridge, Illinois, 60068, United States

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Advocate Outpatient Center - Oak Lawn
RECRUITING

Oak Lawn, Illinois, 60453, United States

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Advocate Sherman Hospital
RECRUITING

Elgin, Illinois, 60123, United States

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Advocate South Suburban Hospital
RECRUITING

Hazel Crest, Illinois, 60429, United States

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Atrium Medical Center-Middletown Regional Hospital
RECRUITING

Franklin, Ohio, 45005-1066, United States

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Aurora Bay Area Medical Group-Marinette
RECRUITING

Marinette, Wisconsin, 54143, United States

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Aurora BayCare Medical Center
RECRUITING

Green Bay, Wisconsin, 54311, United States

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Aurora Cancer Care-Grafton
RECRUITING

Grafton, Wisconsin, 53024, United States

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Aurora Cancer Care-Kenosha South
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Kenosha, Wisconsin, 53142, United States

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Aurora Cancer Care-Milwaukee
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Milwaukee, Wisconsin, 53209, United States

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Aurora Cancer Care-Milwaukee West
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Wauwatosa, Wisconsin, 53226, United States

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Aurora Cancer Care-Racine
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Racine, Wisconsin, 53406, United States

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Aurora Cancer Care-Southern Lakes VLCC
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Burlington, Wisconsin, 53105, United States

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Aurora Health Care Germantown Health Center
RECRUITING

Germantown, Wisconsin, 53022, United States

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Aurora Medical Center in Summit
RECRUITING

Summit, Wisconsin, 53066, United States

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Aurora Saint Luke's Medical Center
RECRUITING

Milwaukee, Wisconsin, 53215, United States

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Aurora Saint Luke's South Shore
RECRUITING

Cudahy, Wisconsin, 53110, United States

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Aurora Sinai Medical Center
RECRUITING

Milwaukee, Wisconsin, 53233, United States

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Aurora West Allis Medical Center
RECRUITING

West Allis, Wisconsin, 53227, United States

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Avera Cancer Institute
RECRUITING

Sioux Falls, South Dakota, 57105, United States

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Avera Cancer Institute - Mitchell
RECRUITING

Mitchell, South Dakota, 57301, United States

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Avera Cancer Institute at Pierre
RECRUITING

Pierre, South Dakota, 57501, United States

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Avera Cancer Institute at Yankton
RECRUITING

Yankton, South Dakota, 57078, United States

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Benefis Sletten Cancer Institute
RECRUITING

Great Falls, Montana, 59405, United States

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Billings Clinic Cancer Center
RECRUITING

Billings, Montana, 59101, United States

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Boston Medical Center
RECRUITING

Boston, Massachusetts, 02118, United States

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Bozeman Health Deaconess Hospital
RECRUITING

Bozeman, Montana, 59715, United States

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Cancer Care Center of O'Fallon
RECRUITING

O'Fallon, Illinois, 62269, United States

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Cancer Care Specialists of Illinois - Decatur
RECRUITING

Decatur, Illinois, 62526, United States

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Cancer Care and Hematology-Fort Collins
RECRUITING

Fort Collins, Colorado, 80528, United States

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Cancer Centers of Southwest Oklahoma Research
RECRUITING

Lawton, Oklahoma, 73505, United States

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Cancer Hematology Centers - Flint
RECRUITING

Flint, Michigan, 48503, United States

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Community Hospital of Anaconda
RECRUITING

Anaconda, Montana, 59711, United States

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Community Medical Center
RECRUITING

Missoula, Montana, 59804, United States

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Condell Memorial Hospital
RECRUITING

Libertyville, Illinois, 60048, United States

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Crossroads Cancer Center
RECRUITING

Effingham, Illinois, 62401, United States

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Dartmouth Cancer Center - North
RECRUITING

Saint Johnsbury, Vermont, 05819, United States

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Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
RECRUITING

Lebanon, New Hampshire, 03756, United States

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Decatur Memorial Hospital
RECRUITING

Decatur, Illinois, 62526, United States

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Fairview Southdale Hospital
RECRUITING

Edina, Minnesota, 55435, United States

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FirstHealth of the Carolinas-Moore Regional Hospital
RECRUITING

Pinehurst, North Carolina, 28374, United States

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Fremont - Rideout Cancer Center
RECRUITING

Marysville, California, 95901, United States

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Genesee Hematology Oncology PC
SUSPENDED

Flint, Michigan, 48503, United States
Genesys Hurley Cancer Institute
RECRUITING

Flint, Michigan, 48503, United States

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Glens Falls Hospital
RECRUITING

Glens Falls, New York, 12801, United States

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Gundersen Lutheran Medical Center
RECRUITING

La Crosse, Wisconsin, 54601, United States

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HaysMed
RECRUITING

Hays, Kansas, 67601, United States

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Hurley Medical Center
RECRUITING

Flint, Michigan, 48503, United States

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Illinois CancerCare-Macomb
RECRUITING

Macomb, Illinois, 61455, United States

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Illinois CancerCare-Peoria
RECRUITING

Peoria, Illinois, 61615, United States

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Jefferson Cherry Hill Hospital
RECRUITING

Cherry Hill, New Jersey, 08002, United States

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Jefferson Torresdale Hospital
RECRUITING

Philadelphia, Pennsylvania, 19114, United States

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Kootenai Clinic Cancer Services - Post Falls
RECRUITING

Post Falls, Idaho, 83854, United States

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Kootenai Clinic Cancer Services - Sandpoint
RECRUITING

Sandpoint, Idaho, 83864, United States

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Kootenai Health - Coeur d'Alene
RECRUITING

Coeur d'Alene, Idaho, 83814, United States

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Lake Regional Hospital
RECRUITING

Osage Beach, Missouri, 65065, United States

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Lawrence Memorial Hospital
RECRUITING

Lawrence, Kansas, 66044, United States

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Lehigh Valley Hospital - Muhlenberg
RECRUITING

Bethlehem, Pennsylvania, 18017, United States

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Lehigh Valley Hospital-Cedar Crest
RECRUITING

Allentown, Pennsylvania, 18103, United States

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Logan Health Medical Center
RECRUITING

Kalispell, Montana, 59901, United States

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Lutheran Hospital - Cancer Centers of Colorado
RECRUITING

Golden, Colorado, 80401, United States

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Margaret R Pardee Memorial Hospital
RECRUITING

Hendersonville, North Carolina, 28791, United States

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Marshfield Medical Center - Weston
RECRUITING

Weston, Wisconsin, 54476, United States

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Marshfield Medical Center-EC Cancer Center
RECRUITING

Eau Claire, Wisconsin, 54701, United States

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Marshfield Medical Center-River Region at Stevens Point
RECRUITING

Stevens Point, Wisconsin, 54482, United States

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Mary Greeley Medical Center
RECRUITING

Ames, Iowa, 50010, United States

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McFarland Clinic - Ames
RECRUITING

Ames, Iowa, 50010, United States

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McFarland Clinic - Boone
SUSPENDED

Boone, Iowa, 50036, United States
McFarland Clinic - Jefferson
SUSPENDED

Jefferson, Iowa, 50129, United States
McFarland Clinic - Marshalltown
RECRUITING

Marshalltown, Iowa, 50158, United States

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McFarland Clinic - Trinity Cancer Center
RECRUITING

Fort Dodge, Iowa, 50501, United States

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Medical Center of the Rockies
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Loveland, Colorado, 80538, United States

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Medical University of South Carolina
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Charleston, South Carolina, 29425, United States

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Memorial Hospital East
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Shiloh, Illinois, 62269, United States

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Memorial Hospital North
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Colorado Springs, Colorado, 80920, United States

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Memorial Sloan Kettering Basking Ridge
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Basking Ridge, New Jersey, 07920, United States

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Memorial Sloan Kettering Bergen
RECRUITING

Montvale, New Jersey, 07645, United States

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Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States

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Memorial Sloan Kettering Commack
RECRUITING

Commack, New York, 11725, United States

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Memorial Sloan Kettering Monmouth
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Middletown, New Jersey, 07748, United States

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Memorial Sloan Kettering Nassau
RECRUITING

Uniondale, New York, 11553, United States

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Memorial Sloan Kettering Westchester
RECRUITING

Harrison, New York, 10604, United States

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Mercy Hospital
RECRUITING

Cedar Rapids, Iowa, 52403, United States

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Mercy Hospital
RECRUITING

Coon Rapids, Minnesota, 55433, United States

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Mercy Hospital South
RECRUITING

St Louis, Missouri, 63128, United States

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Miami Valley Cancer Care and Infusion
RECRUITING

Greenville, Ohio, 45331, United States

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Miami Valley Hospital
RECRUITING

Dayton, Ohio, 45409, United States

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Miami Valley Hospital North
RECRUITING

Dayton, Ohio, 45415, United States

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Miami Valley Hospital South
RECRUITING

Centerville, Ohio, 45459, United States

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Minnesota Oncology - Burnsville
RECRUITING

Burnsville, Minnesota, 55337, United States

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Mount Sinai Medical Center
SUSPENDED

Miami Beach, Florida, 33140, United States
Oncology Associates at Mercy Medical Center
RECRUITING

Cedar Rapids, Iowa, 52403, United States

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Park Nicollet Clinic - Saint Louis Park
RECRUITING

Saint Louis Park, Minnesota, 55416, United States

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Pocono Medical Center
RECRUITING

East Stroudsburg, Pennsylvania, 18301, United States

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Poudre Valley Hospital
RECRUITING

Fort Collins, Colorado, 80524, United States

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ProHealth D N Greenwald Center
RECRUITING

Mukwonago, Wisconsin, 53149, United States

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ProHealth Oconomowoc Memorial Hospital
RECRUITING

Oconomowoc, Wisconsin, 53066, United States

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ProHealth Waukesha Memorial Hospital
RECRUITING

Waukesha, Wisconsin, 53188, United States

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ProMedica Flower Hospital
RECRUITING

Sylvania, Ohio, 43560, United States

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Providence Portland Medical Center
RECRUITING

Portland, Oregon, 97213, United States

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Providence Saint Vincent Medical Center
RECRUITING

Portland, Oregon, 97225, United States

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Providence Willamette Falls Medical Center
RECRUITING

Oregon City, Oregon, 97045, United States

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Regions Hospital
RECRUITING

Saint Paul, Minnesota, 55101, United States

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SUNY Upstate Medical Center-Community Campus
RECRUITING

Syracuse, New York, 13215, United States

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Saint Alphonsus Cancer Care Center-Boise
RECRUITING

Boise, Idaho, 83706, United States

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Saint Alphonsus Cancer Care Center-Caldwell
RECRUITING

Caldwell, Idaho, 83605, United States

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Saint Alphonsus Cancer Care Center-Nampa
RECRUITING

Nampa, Idaho, 83687, United States

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Saint Alphonsus Cancer Care Center-Ontario
RECRUITING

Ontario, Oregon, 97914, United States

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Saint Francis Medical Center
RECRUITING

Cape Girardeau, Missouri, 63703, United States

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Saint John's Hospital - Healtheast
RECRUITING

Maplewood, Minnesota, 55109, United States

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Salina Regional Health Center
RECRUITING

Salina, Kansas, 67401, United States

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Sanford Bismarck Medical Center
RECRUITING

Bismarck, North Dakota, 58501, United States

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Sanford Broadway Medical Center
RECRUITING

Fargo, North Dakota, 58122, United States

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Sanford Cancer Center Oncology Clinic
RECRUITING

Sioux Falls, South Dakota, 57104, United States

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Sanford Joe Lueken Cancer Center
RECRUITING

Bemidji, Minnesota, 56601, United States

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Sanford Roger Maris Cancer Center
RECRUITING

Fargo, North Dakota, 58122, United States

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Sanford USD Medical Center - Sioux Falls
RECRUITING

Sioux Falls, South Dakota, 57117-5134, United States

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Sidney Kimmel Cancer Center Washington Township
RECRUITING

Sewell, New Jersey, 08080, United States

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Siteman Cancer Center at Christian Hospital
RECRUITING

St Louis, Missouri, 63136, United States

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Siteman Cancer Center at Saint Peters Hospital
RECRUITING

City of Saint Peters, Missouri, 63376, United States

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Siteman Cancer Center at West County Hospital
RECRUITING

Creve Coeur, Missouri, 63141, United States

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Siteman Cancer Center-South County
RECRUITING

St Louis, Missouri, 63129, United States

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Southern Illinois University School of Medicine
RECRUITING

Springfield, Illinois, 62702, United States

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Springfield Clinic
RECRUITING

Springfield, Illinois, 62702, United States

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Springfield Memorial Hospital
RECRUITING

Springfield, Illinois, 62781, United States

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State University of New York Upstate Medical University
RECRUITING

Syracuse, New York, 13210, United States

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The University of Kansas Cancer Center - Olathe
RECRUITING

Olathe, Kansas, 66061, United States

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Trinity Health IHA Medical Group Hematology Oncology - Brighton
RECRUITING

Brighton, Michigan, 48114, United States

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Trinity Health IHA Medical Group Hematology Oncology - Canton
RECRUITING

Canton, Michigan, 48188, United States

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Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
RECRUITING

Chelsea, Michigan, 48118, United States

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Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
RECRUITING

Ypsilanti, Michigan, 48197, United States

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Trinity Health Saint Joseph Mercy Hospital Ann Arbor
RECRUITING

Ann Arbor, Michigan, 48106, United States

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Trinity Health Saint Joseph Mercy Oakland Hospital
RECRUITING

Pontiac, Michigan, 48341, United States

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Trinity Health Saint Mary Mercy Livonia Hospital
RECRUITING

Livonia, Michigan, 48154, United States

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UC Comprehensive Cancer Center at Silver Cross
RECRUITING

New Lenox, Illinois, 60451, United States

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UCHealth Greeley Hospital
RECRUITING

Greeley, Colorado, 80631, United States

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UCHealth Memorial Hospital Central
RECRUITING

Colorado Springs, Colorado, 80909, United States

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UChicago Medicine Northwest Indiana
RECRUITING

Crown Point, Indiana, 46307, United States

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UNC Lineberger Comprehensive Cancer Center
RECRUITING

Chapel Hill, North Carolina, 27599, United States

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UW Cancer Center at ProHealth Care
RECRUITING

Waukesha, Wisconsin, 53188, United States

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UW Health Carbone Cancer Center Rockford
RECRUITING

Rockford, Illinois, 61114, United States

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United Hospital
RECRUITING

Saint Paul, Minnesota, 55102, United States

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University Health Truman Medical Center
RECRUITING

Kansas City, Missouri, 64108, United States

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University of Arkansas for Medical Sciences
RECRUITING

Little Rock, Arkansas, 72205, United States

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University of Chicago Comprehensive Cancer Center
RECRUITING

Chicago, Illinois, 60637, United States

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University of Chicago Medicine-Orland Park
RECRUITING

Orland Park, Illinois, 60462, United States

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University of Kansas Cancer Center
RECRUITING

Kansas City, Kansas, 66160, United States

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University of Kansas Cancer Center - Briarcliff
RECRUITING

Kansas City, Missouri, 64116, United States

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University of Kansas Cancer Center - Lee's Summit
RECRUITING

Lee's Summit, Missouri, 64064, United States

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University of Kansas Cancer Center - North
RECRUITING

Kansas City, Missouri, 64154, United States

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University of Kansas Cancer Center-Overland Park
RECRUITING

Overland Park, Kansas, 66210, United States

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University of Kansas Health System Saint Francis Campus
RECRUITING

Topeka, Kansas, 66606, United States

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Contact Phone: •••-•••-••••
University of Kansas Hospital-Indian Creek Campus
RECRUITING

Overland Park, Kansas, 66211, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Kansas Hospital-Westwood Cancer Center
RECRUITING

Westwood, Kansas, 66205, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Maryland/Greenebaum Cancer Center
RECRUITING

Baltimore, Maryland, 21201, United States

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Contact Phone: •••-•••-••••
University of Michigan Health - Sparrow Lansing
RECRUITING

Lansing, Michigan, 48912, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Oklahoma Health Sciences Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States

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Upper Valley Medical Center
RECRUITING

Troy, Ohio, 45373, United States

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Upstate Cancer Center at Verona
RECRUITING

Verona, New York, 13478, United States

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VA Palo Alto Health Care System
SUSPENDED

Palo Alto, California, 94304, United States
VCU Massey Cancer Center at Stony Point
RECRUITING

Richmond, Virginia, 23235, United States

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Contact Email: •••••@•••••
VCU Massey Comprehensive Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
Vince Lombardi Cancer Clinic - Oshkosh
RECRUITING

Oshkosh, Wisconsin, 54904, United States

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Vince Lombardi Cancer Clinic-Sheboygan
RECRUITING

Sheboygan, Wisconsin, 53081, United States

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Vince Lombardi Cancer Clinic-Two Rivers
RECRUITING

Two Rivers, Wisconsin, 54241, United States

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Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
West Virginia University Charleston Division
RECRUITING

Charleston, West Virginia, 25304, United States

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Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.