New Two-Drug attack on tough head and neck cancers

NCT ID NCT05172258

Summary

This study is testing if adding a new drug called ipatasertib to a standard immunotherapy (pembrolizumab) works better for controlling advanced head and neck cancer that has returned or spread. It will involve about 52 adults who have not yet received treatment for their advanced cancer. The main goal is to see if the drug combination can keep the cancer from growing for a longer time compared to the standard treatment alone.

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Contacts and locations

Locations

  • City of Hope Antelope Valley

    Lancaster, California, 93534, United States

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

  • City of Hope at Irvine Lennar

    Irvine, California, 92618, United States

  • Keck Medicine of USC Koreatown

    Los Angeles, California, 90020, United States

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    New York, New York, 10016, United States

  • Los Angeles General Medical Center

    Los Angeles, California, 90033, United States

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Montefiore Medical Center - Moses Campus

    The Bronx, New York, 10467, United States

  • Montefiore Medical Center-Einstein Campus

    The Bronx, New York, 10461, United States

  • NYP/Weill Cornell Medical Center

    New York, New York, 10065, United States

  • NYU Langone Hospital - Long Island

    Mineola, New York, 11501, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Stanford Cancer Institute Palo Alto

    Palo Alto, California, 94304, United States

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • USC Norris Oncology/Hematology-Newport Beach

    Newport Beach, California, 92663, United States

  • University of California Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States

  • University of Kentucky/Markey Cancer Center

    Lexington, Kentucky, 40536, United States

  • University of Texas Medical Branch

    Galveston, Texas, 77555-0565, United States

  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center

    Madison, Wisconsin, 53718, United States

  • University of Wisconsin Carbone Cancer Center - University Hospital

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.