Personalized vaccine trial aims to train immune system to fight cancer recurrence

NCT ID NCT04183166

Summary

This trial is testing a personalized immunotherapy called TG4050 in patients with advanced head and neck cancer who have completed initial treatment. The goal is to see if this vaccine, designed to target each patient's specific cancer mutations, is safe and can help prevent the cancer from coming back. The study will compare outcomes between patients receiving the vaccine and those receiving standard monitoring alone.

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Contacts and locations

Locations

  • Aintree University Hospital NHS Fondation Trust

    Liverpool, L9 7AL, United Kingdom

  • Complejo Hospitalario Universitario de Santiago

    Santiago de Compostela, 15076, Spain

  • Hospital Clínico San Carlos

    Madrid, 28040, Spain

  • Hospital Regional Universitario de Málaga - Hospital Civil

    Málaga, 29010, Spain

  • Hospital Universitari Vall d Hebrón

    Barcelona, 08035, Spain

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

  • Hôpital Saint André - CHU de Bordeaux

    Bordeaux, 33000, France

  • Hôpital de la Timone

    Marseille, 13000, France

  • IUCT Toulouse

    Toulouse, 31100, France

  • Institut Català d Oncologia - Hospital Duran i Reynals

    Barcelona, 08908, Spain

  • Institut Curie

    Paris, 75005, France

  • Institut Gustave Roussy

    Villejuif, 94805, France

  • Mayo Clinic Jacksonville

    Jacksonville, Florida, 32224, United States

  • NHS Clatterbridge Cancer Center

    Liverpool, L7 8YA, United Kingdom

Conditions

Explore the condition pages connected to this study.