Gene variant may explain why some People's 'Good' cholesterol works better
NCT ID NCT03109067
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at how a common gene variation (TaqIB) affects the function of HDL, or 'good' cholesterol, after a meal. Researchers compared two groups of healthy men with different versions of this gene to see how well their HDL could remove cholesterol from cells. The goal was to better understand why some people are more protected from heart disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help explain why some people have better heart protection from HDL cholesterol, potentially guiding future personalized prevention strategies.
- What could go wrong
- This is a small, completed observational study in healthy men only. It does not test a treatment, so it cannot directly lead to a new therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre d'Investigation Clinique Paris Est
Paris, 75013, France
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