Blood markers could transform liver cancer surveillance
NCT ID NCT05148572
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This study follows people with liver cancer who are scheduled for surgery, measuring tiny molecules called microRNAs in their blood before and after the operation. The goal is to find patterns that could signal whether the cancer has come back. Researchers will also look at gut bacteria and other substances in urine and blood to build a more complete picture. If these markers prove reliable, they might one day replace or improve current screening methods, which miss many early-stage liver cancers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple blood test that detects liver cancer earlier and predicts recurrence after surgery.
- What could go wrong
- This is an observational study with only 101 participants, so findings may not apply to all patients. The biomarkers need further validation before they can be used in practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Changi General Hospital
Singapore, 529889, Singapore
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National Cancer Centre Singapore
Singapore, 168583, Singapore
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National University Hospital
Singapore, 119228, Singapore
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Sengkang General Hospital
Singapore, 544886, Singapore
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Singapore General Hospital
Singapore, 169608, Singapore
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Tan Tock Seng Hospital
Singapore, 308433, Singapore
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