New hope for sickle cell: Half-Matched transplants aim for 90% success
NCT ID NCT07616154
First seen Jun 09, 2026 · Last updated Jun 09, 2026
Summary
This study tests a new approach to bone marrow transplant for children and young adults with sickle cell disease. Instead of a fully matched donor, it uses a half-matched family donor and a milder chemotherapy regimen to reduce side effects. The goal is to prevent graft rejection and severe graft-versus-host disease, aiming for over 90% of participants to be alive and free of these complications one year after transplant. Up to 45 participants will be enrolled.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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St Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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