New gel could treat implant gum disease without surgery
NCT ID NCT07680491
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study tests a non-surgical treatment called H42 for people with deep gum pockets around dental implants (peri-implantitis). Half of the 56 participants receive H42, while the other half serve as a control group. Researchers measure pocket depth, plaque, inflammation, pain, and bone changes over three months to see if H42 helps heal the gums and preserve bone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
H42
What this could lead to
If successful, H42 could offer a non-surgical option to manage peri-implantitis, potentially reducing the need for more invasive procedures.
What could go wrong
This is a small, early-stage study with only 56 participants, so results may not apply broadly. The treatment may not significantly improve pocket depth or bone levels.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- 10-Year Follow-Up of Peri-Implantitis Surgery (NCT07678892)
- Long-Term Follow-Up of Peri-Implantitis Surgery NCT06648564
- Periodontitis Grading & Implant Health: 60-Month NCT07671456
- Peri-Implantitis Surgery: Soft Tissue Graft Tria NCT04323540
- Peri-Implantitis Trial: Electrolytic Cleaning vs NCT07644975
- Dermal Matrix for Peri-Implantitis Repair – NCT06398288
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Faculty of Dentistry, University of Seville
RECRUITINGSeville, 41009, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••