New drug combo may reduce transplant complications in blood cancer patients

NCT ID NCT01231412

First seen May 06, 2026 · Last updated May 06, 2026

Summary

This study tested different combinations of immune-suppressing drugs to prevent graft-versus-host disease (GVHD) in 174 patients with blood cancers who received a stem cell transplant from an unrelated donor. The goal was to find the most effective approach to reduce severe GVHD, a common and serious complication. Patients received chemotherapy and radiation before transplant, followed by one of several drug regimens. The results help guide better post-transplant care.

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Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, 8200, Denmark

  • Emory University/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

  • Huntsman Cancer Institute/University of Utah

    Salt Lake City, Utah, 84112, United States

  • Medizinische Univ Klinik Koln

    Cologne, 50924, Germany

  • Presbyterian - Saint Lukes Medical Center - Health One

    Denver, Colorado, 80218, United States

  • Rigshospitalet University Hospital

    Copenhagen, 2100, Denmark

  • Universitaet Leipzig

    Leipzig, D-04103, Germany

  • University of Colorado

    Denver, Colorado, 80217-3364, United States

  • University of Tuebingen-Germany

    Tübingen, D-72076, Germany

  • VA Puget Sound Health Care System

    Seattle, Washington, 98101, United States

Conditions

Explore the condition pages connected to this study.