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Gut check: can exercise change your diabetes bacteria?

NCT ID NCT06268743

Knowledge-focused Sponsor: University of New Brunswick Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
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Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how different levels of exercise change the bacteria in the gut of people with type 2 diabetes. Forty adults with type 2 diabetes did either moderate or high-intensity endurance and strength training for 16 weeks. Researchers compared changes in blood sugar and gut bacteria between the two groups to learn more about how exercise affects health.

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Feb 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 64 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 19 - 64 years old; * Diagnosed with type 2 diabetes; * An HbA1c \>= 7.0%; * Not currently meeting the recommended levels of physical activity for optimal health (i.e., 150 minutes of moderate-to-vigorous physical activity and 2+ days/week of resistance training); * Average less than 10,000 steps per day over the last seven days; * No change in diabetes medications over the last three months. Exclusion Criteria: * Not diagnosed with type 2 diabetes; * Partaking in a self-reported regular exercise regimen, defined as consistent participation in running or jogging activity, attending exercise classes every week, or averaging 10,000 steps per day or more over seven days; * Currently performing two days of resistance training per week; * Having an injury that would prevent safe participation in the intervention; * A self-reported diagnosis of low iron concentrations, anemia, or being treated for these conditions; * A diagnosis of any red blood cell altering condition (i.e., sickle cell anemia, poikilocytosis); * Currently living with any cardiovascular disease which would impact the ability to participate in exercise safely; * Currently prescribed any medication which would impact the ability to use a heart rate monitor to accurately track intensity.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Motor Activity type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Type 2 diabetes

Contacts and locations

Locations

  • Cardiometabolic Exercise & Lifestyle Laboratory

    Fredericton, New Brunswick, E3B5A3, Canada

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