Gut hormone shot aims to strengthen fragile bones in kids with muscle diseases
NCT ID NCT07254988
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether two gut hormones, GIP and GLP-2, could reduce bone breakdown in children with spinal muscular atrophy, cerebral palsy, or Duchenne muscular dystrophy who use wheelchairs. Participants received a liquid meal and then either a hormone injection or a placebo. The trial was terminated early and only enrolled 3 children, so no firm conclusions can be drawn.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- GIP and GLP-2 (gut hormones given as injection)
- What this could lead to
- If it worked, this could point toward a new way to protect bone health in children with muscle-weakening disorders.
- What could go wrong
- The study was terminated early with only 3 participants, so results are very limited. It is unclear if these hormones will have the same effect in children as in healthy adults.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Rigshospitalet
Copenhagen, Denmark
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Other studies related to the condition(s) this trial covers.
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