Gut bugs may decide if your statin works
NCT ID NCT04098003
First seen Jun 25, 2026 · Last updated Jul 10, 2026 · Updated 3 times
Summary
This study looks at how the bacteria living in your gut might change how well the cholesterol-lowering drug rosuvastatin (Crestor) works. Researchers will give healthy volunteers either the drug or a placebo for eight weeks and track changes in gut bacteria and cholesterol levels. The goal is to understand why some people respond better to statins than others.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Rosuvastatin (Crestor)
- What this could lead to
- If successful, this could help doctors predict who will benefit most from statins based on their gut bacteria.
- What could go wrong
- This is a small, early-stage study in healthy people, not those with high cholesterol. Results may not apply to patients or lead to immediate changes in treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Pennsylvania
Phildelphia, Pennsylvania, 19104, United States
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