Gut check: could probiotics help kids with autism handle stress?

NCT ID NCT06269614

Ongoing Knowledge-focused Sponsor: Nova Southeastern University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the gut microbiome (the bacteria in our intestines) is linked to stress in children with autism or those who have experienced trauma. Researchers will give 75 children, ages 4 to 7, a probiotic powder for 4 weeks and measure changes in their gut bacteria and stress hormone levels. The goal is to better understand the connection between the gut and brain, not to test a treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Probiotic (dietary supplement)
What this could lead to: If successful, this could help us understand whether changing gut bacteria might help children with autism or stress manage their reactions better.
What could go wrong: This is a small, early-stage study with no control group for the probiotic. Results may not apply to all children, and the probiotic may cause mild digestive upset.

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder Fractures, Stress

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVERSE CHILDHOOD EXPERIENCES AUTISM SPECTRUM DISORDER STRESS REACTION

Contacts and locations

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Locations

Nova Southeastern University College of Nursing

Davie, Florida, 33314, United States

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