Gut check: scientists hunt for microbe links between IBD and depression

NCT ID NCT07252427

Recruiting now Knowledge-focused Sponsor: Fang Tang Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at gut bacteria and related chemicals in 120 adults to understand why inflammatory bowel disease (IBD) and depression often occur together. Researchers will compare people with both conditions, those with IBD only, and healthy volunteers. The goal is to find unique microbial or metabolic patterns that could explain the connection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could reveal specific gut bacteria or molecules linked to both IBD and depression, pointing toward future treatment targets.
What could go wrong: This is an observational study, not a treatment trial. It will not directly test any therapy, and findings may not lead to immediate medical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

depressive disorder inflammatory bowel disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSIVE DISORDER INFLAMMATORY BOWEL DISEASE

Contacts and locations

Locations

The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital
RECRUITING

Jinan, Shandong, 250014, China

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