Scientists peek inside the gut to unlock immunotherapy mysteries
NCT ID NCT04600180
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how cancer immunotherapy changes the immune cells in the gut. Researchers will take small tissue samples from the colon and blood samples before and during treatment in 38 patients. The goal is to better understand gut-related side effects, not to test a new drug.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors understand why some patients develop gut side effects from immunotherapy and how to predict or prevent them.
What could go wrong
This is a small, early exploratory study with only 38 participants. It is not testing a treatment, so it will not directly benefit participants or change cancer care immediately.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University Medical Center Groningen
Groningen, 9713 GZ, Netherlands