Could a daily synbiotic capsule ease emotional and gut symptoms in ADHD?
NCT ID NCT07717359
First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time
Summary
This study investigates whether a synbiotic supplement—a mix of probiotics and prebiotics—can improve emotion regulation and reduce gastrointestinal problems in adults with ADHD. Participants take either the synbiotic or a placebo capsule daily for 12 weeks. The main focus is on changes in emotional control and gut symptoms, exploring the connection between the gut and the brain.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a synbiotic supplement (probiotic bacteria and prebiotics) in capsule form
- What this could lead to
- If it works, this could point toward a simple dietary supplement that helps adults with ADHD manage emotional symptoms and stomach discomfort.
- What could go wrong
- This is an early-stage trial with a moderate number of participants, and the supplement may show no benefit over placebo. Results may not apply to everyone with ADHD.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 174 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 64 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ADHD-diagnosis * Self-described gastrointestinal problems * Has not previously consumed Synbiotics * Be prepared to avoid supplements with lactic acid bacteria, calcium and vitamin B6, B9, and B12, starting from washout Exclusion Criteria: * Has consumed antibiotics within the previous 6 weeks * Has a serious disease that requires treatment and/or leads to a weakened immune system
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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