Gut bacteria may supercharge cancer immunotherapy, early trial hints

NCT ID NCT03595683

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 29 times

Summary

This study tested whether taking a pill containing special gut bacteria (EDP1503) could make standard immunotherapy (pembrolizumab) work better for people with advanced melanoma. Eight adults with melanoma that could not be removed by surgery or had spread took the bacteria pill for two weeks, then added the immunotherapy. The study was stopped early, so results are limited. It aimed to see if the combination could shrink tumors more than immunotherapy alone.

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Contacts and locations

Locations

  • University of Chicago Medical Center

    Chicago, Illinois, 60637, United States

Conditions

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