Gum surgery recovery boosted by Platelet-Rich fibrin and hyaluronic acid?

NCT ID NCT06865092

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether injectable platelet-rich fibrin (i-PRF), titanium platelet-rich fibrin (t-PRF), or hyaluronic acid gel can improve wound healing after gum surgery for overgrown gums. Sixty healthy adults were randomly assigned to one of four groups. Researchers measured pain, burning, and healing at several time points over 28 days. The goal is to find a way to help gums heal faster and more comfortably.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

injectable platelet-rich fibrin (i-PRF), titanium platelet-rich fibrin (t-PRF), and 0.8% hyaluronic acid gel

What this could lead to

If successful, these treatments could speed up gum healing and reduce pain after gum surgery.

What could go wrong

This is a small, completed study with 60 participants. Results may not apply to everyone, and the treatments are not yet proven to be better than standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gingival overgrowth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sağlık Bilimleri Üniversitesi Gülhane Diş Hekimliği Fakültesi

    Ankara, 06010, Turkey (Türkiye)