Can a probiotic stop UTIs from coming back? new study investigates
NCT ID NCT07234227
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a vaginal probiotic containing Lactobacillus crispatus, a 'good' bacteria, in women with recurrent urinary tract infections (UTIs). Over 150 participants will use the probiotic for 3 months, and researchers will measure how well the bacteria colonize the vagina and urine. The goal is to understand if this approach can help restore a healthy microbiome and potentially reduce UTI risk.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Lactobacillus crispatus probiotic (vaginal insert)
- What this could lead to
- If successful, this could point toward a simple probiotic treatment to prevent recurrent UTIs by restoring healthy vaginal and urinary bacteria.
- What could go wrong
- This is an early Phase 1 study focused on bacterial colonization, not on preventing UTIs directly. The probiotic may not colonize effectively or reduce infections, and results may not apply to all women.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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