Can a blood pressure drug ease opioid-related pain?
NCT ID NCT02192398
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether adding guanfacine to opioid painkillers could reverse the extra pain sensitivity that long-term opioid use can cause. It involved 8 adults with chronic neck or back pain who were already taking opioids. The study was terminated early, so results are limited.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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MGH Center for Translational Pain Research
Boston, Massachusetts, 02114, United States