Can a blood pressure drug ease opioid-related pain?
NCT ID NCT02192398
First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times
Summary
This study looked at whether adding guanfacine to opioid painkillers could reverse the extra pain sensitivity that long-term opioid use can cause. It involved 8 adults with chronic neck or back pain who were already taking opioids. The study was terminated early, so results are limited.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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MGH Center for Translational Pain Research
Boston, Massachusetts, 02114, United States
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